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来自第 9 届国际肝脏磁共振成像论坛的共识报告:钆塞酸增强成像的应用。

Consensus report from the 9 International Forum for Liver Magnetic Resonance Imaging: applications of gadoxetic acid-enhanced imaging.

机构信息

Department of Diagnostic Radiology, Royal Marsden Hospital, Sutton, UK.

Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.

出版信息

Eur Radiol. 2021 Aug;31(8):5615-5628. doi: 10.1007/s00330-020-07637-4. Epub 2021 Feb 1.

Abstract

OBJECTIVES

The 9th International Forum for Liver Magnetic Resonance Imaging (MRI) was held in Singapore in September 2019, bringing together radiologists and allied specialists to discuss the latest developments in and formulate consensus statements for liver MRI, including the applications of gadoxetic acid-enhanced imaging.

METHODS

As at previous Liver Forums, the meeting was held over 2 days. Presentations by the faculty on days 1 and 2 and breakout group discussions on day 1 were followed by delegate voting on consensus statements presented on day 2. Presentations and discussions centered on two main meeting themes relating to the use of gadoxetic acid-enhanced MRI in primary liver cancer and metastatic liver disease.

RESULTS AND CONCLUSIONS

Gadoxetic acid-enhanced MRI offers the ability to monitor response to systemic therapy and to assist in pre-surgical/pre-interventional planning in liver metastases. In hepatocellular carcinoma, gadoxetic acid-enhanced MRI provides precise staging information for accurate treatment decision-making and follow-up post therapy. Gadoxetic acid-enhanced MRI also has potential, currently investigational, indications for the functional assessment of the liver and the biliary system. Additional voting sessions at the Liver Forum debated the role of multidisciplinary care in the management of patients with liver disease, evidence to support the use of abbreviated imaging protocols, and the importance of standardizing nomenclature in international guidelines in order to increase the sharing of scientific data and improve the communication between centers.

KEY POINTS

• Gadoxetic acid-enhanced MRI is the preferred imaging method for pre-surgical or pre-interventional planning for liver metastases after systemic therapy. • Gadoxetic acid-enhanced MRI provides accurate staging of HCC before and after treatment with locoregional/biologic therapies. • Abbreviated protocols for gadoxetic acid-enhanced MRI offer potential time and cost savings, but more evidence is necessary. The use of gadoxetic acid-enhanced MRI for the assessment of liver and biliary function is under active investigation.

摘要

目的

第 9 届国际肝脏磁共振成像(MRI)论坛于 2019 年 9 月在新加坡举行,汇集了放射科医生和相关专家,讨论了肝脏 MRI 的最新进展并制定了共识声明,包括钆塞酸增强成像的应用。

方法

与以往的肝脏论坛一样,本次会议为期两天。第 1 天和第 2 天由教员进行演讲,并在第 1 天进行分组讨论,然后在第 2 天对提出的共识声明进行代表投票。演讲和讨论集中在与原发性肝癌和转移性肝脏疾病中使用钆塞酸增强 MRI 相关的两个主要会议主题上。

结果和结论

钆塞酸增强 MRI 能够监测全身治疗的反应,并协助肝脏转移的术前/介入前规划。在肝细胞癌中,钆塞酸增强 MRI 为准确的治疗决策和治疗后随访提供了精确的分期信息。钆塞酸增强 MRI 还具有用于评估肝脏和胆道系统功能的潜在临床应用,目前正在研究中。在肝脏论坛的其他投票环节中,讨论了多学科护理在肝脏疾病患者管理中的作用、支持使用缩短成像方案的证据,以及在国际指南中标准化命名法的重要性,以增加科学数据的共享并改善中心之间的沟通。

要点

• 在全身治疗后,钆塞酸增强 MRI 是肝脏转移术前或介入前规划的首选成像方法。• 钆塞酸增强 MRI 为 HCC 的治疗前和治疗后提供了准确的分期。• 钆塞酸增强 MRI 的简化方案具有潜在的时间和成本节约优势,但需要更多证据。钆塞酸增强 MRI 用于评估肝脏和胆道功能的应用正在积极研究中。

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