Suppr超能文献

在麻醉犬中评估示波法血压监护仪:与直接测量的一致性和检测低血压的能力。

Evaluation of an oscillometric blood pressure monitor in anesthetized dogs: Agreement with direct measurements and ability to detect hypotension.

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.

Catedra de Farmacologia y Toxicologia, Facultad de Ciencias Agropecuarias, Universidad Catolica de Cordoba, Argentina.

出版信息

Res Vet Sci. 2021 Mar;135:162-166. doi: 10.1016/j.rvsc.2021.01.016. Epub 2021 Jan 24.

Abstract

We evaluated the agreement between oscillometric and direct blood pressure monitors in anesthetized dogs and evaluated the ability of the oscillometric method to detect MAP <60 mmHg. Forty client-owned dogs, three months to 14 years old, 4.6-50.2 kg, under general anesthesia were studied. Systolic (SAP), mean (MAP) and diastolic (DAP) arterial pressures were measured directly via an arterial catheter and with an oscillometric cuff (Cardell Touch monitor). Paired values were compared with mixed effect models. Bias and limits of agreement (LOA) were calculated. The sensitivity and false negative rate to detect hypotension (invasive MAP <60 mmHg) using an oscillometric MAP <60 and < 70 mmHg were calculated. A receiver operating characteristics (ROC) curve was constructed and the area under the curve calculated. SAP and DAP differed between methods (both P < 0.001), but MAP did not (P = 0.5). Bland-Altman plots showed small biases but wide LOA for all variables. The sensitivity to detect hypotension was 40% with a false negative rate of 60% when using an oscillometric MAP <60 mmHg, and 68% and 32%, respectively, with a MAP <70 mmHg. The area under the ROC curve for MAP was 0.82. While the oscillometric MAP did not differ from invasive values, the device failed to recognize hypotensive events when 60 mmHg was used as the threshold to detect hypotension. Higher MAP values increased the ability to correctly recognize hypotension, but at the expense of a higher incidence of false positives.

摘要

我们评估了在麻醉犬中使用示波法和直接血压监测仪的一致性,并评估了示波法检测平均动脉压(MAP)<60mmHg 的能力。研究纳入了 40 只接受全身麻醉的客户拥有的犬,年龄 3 个月至 14 岁,体重 4.6-50.2kg。通过动脉导管和示波袖带(Cardell Touch 监护仪)直接测量收缩压(SAP)、平均动脉压(MAP)和舒张压(DAP)。使用混合效应模型比较配对值。计算偏倚和一致性界限(LOA)。计算使用 MAP <60mmHg 和 <70mmHg 的示波法检测低血压(有创 MAP <60mmHg)的敏感性和假阴性率。构建了受试者工作特征(ROC)曲线并计算了曲线下面积。两种方法的 SAP 和 DAP 均存在差异(均 P<0.001),但 MAP 无差异(P=0.5)。Bland-Altman 图显示所有变量的偏倚较小,但 LOA 较宽。当使用 MAP <60mmHg 作为检测低血压的阈值时,检测低血压的敏感性为 40%,假阴性率为 60%;当使用 MAP <70mmHg 时,敏感性分别为 68%和 32%。ROC 曲线下 MAP 的面积为 0.82。虽然示波法 MAP 与有创值无差异,但当使用 60mmHg 作为检测低血压的阈值时,该设备无法识别低血压事件。较高的 MAP 值提高了正确识别低血压的能力,但代价是假阳性率的增加。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验