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妊娠期呼吸道病毒感染:SARS-CoV-2 及其他相关病毒对后代的影响。

Respiratory viral infections during pregnancy: effects of SARS-CoV-2 and other related viruses over the offspring.

机构信息

Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile.

Millennium Institute of Immunology and Immunotherapy Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Andres Bello University, Santiago, Chile.

出版信息

J Dev Orig Health Dis. 2022 Feb;13(1):3-8. doi: 10.1017/S2040174420001373. Epub 2021 Feb 2.

DOI:10.1017/S2040174420001373
PMID:33526164
Abstract

Little is known about the consequences of viral infection for pregnant woman or for the fetus. This issue became important with the appearance of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The infection with SARS-CoV-2 causes a respiratory syndrome known as COVID-19. The fast spreading around the world and the fact that without a treatment or vaccine humans are completely exposed, converts emerging viral diseases in a significant risk for pregnant women and their infants. At this time, during SARS-CoV-2 pandemics pregnant women are not considered as a risk population and little is known about the effects of viral infections over the offspring although the amount of emerging evidence showing detrimental effects for the mother and the fetus. This issue highlights the importance to understand the effects of viral infections during pregnancy. In this work, we analyze the effects of viral infections, like SARS-CoV-2 and other related viruses during pregnancy over the mother and the consequences for the offspring.

摘要

关于病毒感染对孕妇或胎儿的后果知之甚少。随着严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的出现,这个问题变得重要起来。SARS-CoV-2 感染会引起一种称为 COVID-19 的呼吸道综合征。该病毒在全球迅速传播,而人类没有治疗方法或疫苗,因此完全暴露于病毒之下,这使得新发病毒性疾病对孕妇及其婴儿构成了重大风险。此时,在 SARS-CoV-2 大流行期间,孕妇并不被视为高危人群,尽管越来越多的证据表明病毒感染对母亲和胎儿有不利影响,但关于病毒感染对后代的影响知之甚少。这个问题凸显了了解怀孕期间病毒感染影响的重要性。在这项工作中,我们分析了病毒感染(如 SARS-CoV-2 和其他相关病毒)对孕妇的影响及其对后代的后果。

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