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毛发基质瘤:一种常见的头颈部肿瘤,但罕有报道。

Pilomatrixoma: a common tumour of head and neck, but rarely reported.

机构信息

Oral Medicine and Radiology, Yenepoya Dental College, Mangalore, Karnataka, India

Oral and Maxillofacial Surgery, Yenepoya Dental College, Mangalore, Karnataka, India.

出版信息

BMJ Case Rep. 2021 Feb 1;14(2):e238033. doi: 10.1136/bcr-2020-238033.

Abstract

Pilomatrixoma is a benign subcutaneous tumour arising from the sebaceous glands. Mutation in the CTNNB1 gene is seen, suggesting beta-catenin misregulation may be the cause of pilomatrixoma. The preoperative diagnosis may be improved by the awareness of the fact that pilomatrixoma is a common and benign skin tumour of the head and neck region. It presents as a well-defined mass, which may be firm to hard in consistency, usually attached to the skin, but not to the underlying tissue. The colour of overlying skin appears a reddish-brown tinge, indicating that it could be a case of pilomatrixoma. Here, we report a case of pilomatrixoma of the cheek in a woman along with the CT findings and histopathological appearances. Dental surgeons should consider it as one of the differential diagnosis in superficial head and neck swelling with calcification.

摘要

毛母质瘤是一种起源于皮脂腺的良性皮下肿瘤。CTNNB1 基因突变可见,提示β-连环蛋白失调控可能是毛母质瘤的原因。术前诊断可以通过认识到毛母质瘤是一种常见的良性头颈部皮肤肿瘤来提高。它表现为界限清楚的肿块,质地可为坚实至硬,通常附着于皮肤,但不附着于下面的组织。皮肤表面呈红棕色色调,表明可能是毛母质瘤。在这里,我们报告了一例女性颊部毛母质瘤的病例,并伴有 CT 发现和组织病理学表现。牙医应将其视为伴钙化的头颈部浅表肿胀的鉴别诊断之一。

相似文献

3
Pilomatricoma in the head and neck: CT findings in three patients.头颈部毛发上皮瘤:3例患者的CT表现
J Comput Assist Tomogr. 2000 Mar-Apr;24(2):332-5. doi: 10.1097/00004728-200003000-00028.
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Radiology quiz case 2. Pilomatrixoma.放射学病例测验2. 毛母质瘤。
Arch Otolaryngol Head Neck Surg. 2011 May;137(5):523, 525. doi: 10.1001/archoto.2011.65-a.
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CT of pilomatrixoma in the cheek.脸颊部毛母质瘤的CT表现。
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本文引用的文献

1
Pilomatrixoma (calcifying epithelioma).毛母质瘤(钙化上皮瘤)。
Arch Dermatol. 1961 Apr;83:606-18. doi: 10.1001/archderm.1961.01580100070009.
4
CT of pilomatrixoma in the cheek.脸颊部毛母质瘤的CT表现。
AJNR Am J Neuroradiol. 1998 Aug;19(7):1219-20.
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A clinical review of 209 pilomatricomas.209例毛母质瘤的临床回顾
J Am Acad Dermatol. 1998 Aug;39(2 Pt 1):191-5. doi: 10.1016/s0190-9622(98)70073-8.
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bcl-2 expression in pilomatricoma.毛母质瘤中的bcl-2表达
Am J Dermatopathol. 1997 Jun;19(3):254-7. doi: 10.1097/00000372-199706000-00009.
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Head and neck pilomatrixoma.头颈部毛母质瘤
Am J Otolaryngol. 1996 Mar-Apr;17(2):133-5. doi: 10.1016/s0196-0709(96)90010-1.
8
Clinical and histopathologic spectrum of pilomatricomas in adults.成人毛母质瘤的临床和组织病理学谱
Int J Dermatol. 1994 Oct;33(10):705-8. doi: 10.1111/j.1365-4362.1994.tb01515.x.
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Pilomatrixoma of the cheek: report of case.颊部毛母质瘤:病例报告
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