Wells N J, Blair G K, Magee J F, Whiteman D M
University of British Columbia, Vancouver.
Can J Surg. 1994 Dec;37(6):483-6.
To review recent experience with pilomatrixoma, particularly with respect to diagnosis.
Chart review for an 8-year period.
A university-affiliated children's hospital.
Fifty children with 51 histologically proven pilomatrixomas.
Excision of the lesion.
Clinical presentation, diagnosis and pathological findings.
The clinical presentation was typically that of an asymptomatic superficial mass that increased slowly in size and was located in the head and neck (78%) or chest and upper limbs. In one case the mass increased rapidly over 2 weeks and changed in colour from red to purple with areas of pink and tan. The referring diagnosis was incorrect in 94% of cases, and the preoperative diagnosis was incorrect in 57%. Pathologically the tumours were situated in the dermis or subcutaneous tissue. None were cystic, but several had areas of calcification. None of the tumours recurred after excision, but two patients had multiple lesions at different locations and times.
Pilomatrixomas in children are simple to treat successfully but have variable clinical presentation. Early diagnosis is important so that unnecessary, aggressive surgery can be avoided.
回顾近期毛母质瘤的治疗经验，尤其是在诊断方面。
对8年期间的病历进行回顾。
一家大学附属医院。
50名儿童患有51例经组织学证实的毛母质瘤。
切除病变。
临床表现、诊断及病理结果。
临床表现通常为无症状的浅表肿块，大小缓慢增加，位于头颈部（78%）或胸部及上肢。1例肿块在2周内迅速增大，颜色从红色变为紫色，伴有粉色和棕褐色区域。在94%的病例中，转诊诊断错误，术前诊断错误率为57%。病理检查显示肿瘤位于真皮或皮下组织。无一例为囊性，但有几例有钙化区域。切除后无一例肿瘤复发，但有2例患者在不同部位和时间出现多个病变。
儿童毛母质瘤易于成功治疗，但临床表现多样。早期诊断很重要，这样可以避免不必要的激进手术。
