人类结直肠癌中的瞬时受体电位（TRP）通道：证据与展望。
Transient receptor potential (TRP) channels in human colorectal cancer: evidence and perspectives.
机构信息
Department of Anatomy, Histology and Embryology, School of Medicine, University of Patras, Patras, Greece.
出版信息
Histol Histopathol. 2021 May;36(5):515-526. doi: 10.14670/HH-18-308. Epub 2021 Feb 2.
PMID:33528023
Abstract
Colorectal cancer (CRC) is one of the leading causes of death in the civilized world. Transient receptor potential channels (TRPs) are a heterogeneous family of cation channels that play an important role in gastrointestinal physiology. TRPs have been linked with carcinogenesis in the colon and their role as potential therapeutic targets and prognostic biomarkers is under investigation.
摘要
结直肠癌（CRC）是文明世界主要的死亡原因之一。瞬时受体电位通道（TRP）是阳离子通道的一个异质家族，在胃肠道生理学中发挥着重要作用。TRP 与结肠发生癌变有关，它们作为潜在治疗靶点和预后生物标志物的作用正在研究中。
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