Department of Radiology, Fujita Health University, School of Medicine, Toyoake, Japan.
Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University School of Medicine, Toyoake, Japan.
Br J Radiol. 2022 Apr 1;95(1132):20201053. doi: 10.1259/bjr.20201053. Epub 2021 Feb 2.
Morphological evaluation of the lung is important in the clinical evaluation of pulmonary diseases. However, the disease process, especially in its early phases, may primarily result in changes in pulmonary function without changing the pulmonary structure. In such cases, the traditional imaging approaches to pulmonary morphology may not provide sufficient insight into the underlying pathophysiology. Pulmonary imaging community has therefore tried to assess pulmonary diseases and functions utilizing not only nuclear medicine, but also CT and MR imaging with various technical approaches. In this review, we overview state-of-the art MR methods and the future direction of: (1) ventilation imaging, (2) perfusion imaging and (3) biomechanical evaluation for pulmonary functional imaging.
肺部的形态学评估在肺部疾病的临床评估中非常重要。然而，疾病的发展过程，尤其是在早期阶段，可能主要导致肺功能的变化，而不会改变肺结构。在这种情况下，传统的肺部形态学成像方法可能无法提供对潜在病理生理学的充分了解。因此，肺部成像界不仅尝试利用核医学，还尝试利用各种技术方法的 CT 和 MR 成像来评估肺部疾病和功能。在这篇综述中，我们概述了用于肺部功能成像的最新 MR 方法和未来方向：（1）通气成像，（2）灌注成像和（3）生物力学评估。
