Medical Radiation Science, Faculty of Science and Engineering, Curtin University, Perth, Australia.
Curr Med Imaging. 2021;17(7):820-831. doi: 10.2174/1573405617666210202114336.
When treating superficial tumors with external beam radiation therapy, bolus is often used. Bolus increases surface dose, reduces dose to underlying tissue, and improves dose homogeneity.
The conventional bolus types used clinically in practice have some disadvantages. The use of Three-Dimensional (3D) printing has the potential to create more effective boluses. CT data is used for dosimetric calculations for these treatments and often to manufacture the customized 3D-printed bolus.
The aim of this review is to evaluate the published studies that have compared 3D-printed bolus against conventional bolus types.
A systematic search of several databases and a further appraisal for relevance and eligibility resulted in the 14 articles used in this review. The 14 articles were analyzed based on their comparison of 3D-printed bolus and at least one conventional bolus type.
The findings of this review indicated that 3D-printed bolus has a number of advantages. Compared to conventional bolus types, 3D-printed bolus was found to have equivalent or improved dosimetric measures, positional accuracy, fit, and uniformity. 3D-printed bolus was also found to benefit workflow efficiency through both time and cost effectiveness. However, factors such as patient comfort and staff perspectives need to be further explored to support the use of 3Dprinted bolus in routine practice.
在使用外束放射治疗治疗浅表肿瘤时，常使用填充物。填充物可以增加表面剂量，减少对下层组织的剂量，并改善剂量均匀性。
临床上常规使用的填充物类型存在一些缺点。使用三维（3D）打印技术有潜力制造更有效的填充物。这些治疗通常使用 CT 数据进行剂量计算，并经常用于制造定制的 3D 打印填充物。
本综述的目的是评估已发表的将 3D 打印填充物与常规填充物类型进行比较的研究。
通过对多个数据库进行系统搜索，并进一步评估相关性和资格，共纳入了 14 篇用于本综述的文章。根据其对 3D 打印填充物与至少一种常规填充物类型的比较，对这 14 篇文章进行了分析。
本综述的研究结果表明，3D 打印填充物具有许多优势。与常规填充物类型相比，3D 打印填充物在剂量学测量、位置精度、贴合度和均匀性方面具有同等或更好的效果。3D 打印填充物还通过提高效率（包括时间和成本效益）来改善工作流程。然而，患者舒适度和工作人员观点等因素仍需进一步探讨，以支持 3D 打印填充物在常规实践中的应用。
