Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target.
作者信息
Sainaghi Pier Paolo, Bellan Mattia, Nerviani Alessandra
机构信息
Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara, Italy.
Division of Rheumatology, CAAD (Center for Translational Research on Autoimmune and Allergic Diseases) "AOU Maggiore della Carità", Novara, Italy.
出版信息
Dis Markers. 2021 Jan 13;2021:2854925. doi: 10.1155/2021/2854925. eCollection 2021.
Abstract
摘要
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本文引用的文献
1
Gas6/TAM System: A Key Modulator of the Interplay between Inflammation and Fibrosis.Gas6/TAM 系统：炎症与纤维化相互作用的关键调节因子。
Int J Mol Sci. 2019 Oct 12;20(20):5070. doi: 10.3390/ijms20205070.
2
Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma.多受体酪氨酸激酶的综合分析确定 Axl 为肝细胞癌索拉非尼耐药的治疗靶点和介质。
Br J Cancer. 2019 Mar;120(5):512-521. doi: 10.1038/s41416-018-0373-6. Epub 2019 Feb 15.
3
A high Gas6 level in plasma predicts venous thromboembolism recurrence, major bleeding and mortality in the elderly: a prospective multicenter cohort study.血浆中高 Gas6 水平可预测老年静脉血栓栓塞复发、大出血和死亡：一项前瞻性多中心队列研究。
J Thromb Haemost. 2019 Feb;17(2):306-318. doi: 10.1111/jth.14365.
4
Candidate Biomarkers of Liver Fibrosis: A Concise, Pathophysiology-oriented Review.肝纤维化的候选生物标志物：一篇简明的、以病理生理学为导向的综述。
J Clin Transl Hepatol. 2018 Sep 28;6(3):317-325. doi: 10.14218/JCTH.2018.00006. Epub 2018 Jul 2.
5
Targeting of TAM Receptors Ameliorates Fibrotic Mechanisms in Idiopathic Pulmonary Fibrosis.靶向 TAM 受体可改善特发性肺纤维化中的纤维化机制。
Am J Respir Crit Care Med. 2018 Jun 1;197(11):1443-1456. doi: 10.1164/rccm.201707-1519OC.
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Gas6 as a predictor of esophageal varices in patients affected by hepatitis C virus related-chronic liver disease.Gas6作为丙型肝炎病毒相关慢性肝病患者食管静脉曲张的预测指标。
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The non-invasive serum biomarker soluble Axl accurately detects advanced liver fibrosis and cirrhosis.血清非侵入性生物标志物可溶性 Axl 可准确检测晚期肝纤维化和肝硬化。
Cell Death Dis. 2017 Oct 26;8(10):e3135. doi: 10.1038/cddis.2017.554.
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Gas6 as a putative noninvasive biomarker of hepatic fibrosis.Gas6作为肝纤维化的一种潜在非侵入性生物标志物。
Biomark Med. 2016 Dec;10(12):1241-1249. doi: 10.2217/bmm-2016-0210. Epub 2016 Dec 7.
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