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Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target.

作者信息

Sainaghi Pier Paolo, Bellan Mattia, Nerviani Alessandra

机构信息

Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara, Italy.

Division of Rheumatology, CAAD (Center for Translational Research on Autoimmune and Allergic Diseases) "AOU Maggiore della Carità", Novara, Italy.

出版信息

Dis Markers. 2021 Jan 13;2021:2854925. doi: 10.1155/2021/2854925. eCollection 2021.

Abstract
摘要

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1
Gas6/TAM System: A Key Modulator of the Interplay between Inflammation and Fibrosis.
Int J Mol Sci. 2019 Oct 12;20(20):5070. doi: 10.3390/ijms20205070.
4
Candidate Biomarkers of Liver Fibrosis: A Concise, Pathophysiology-oriented Review.
J Clin Transl Hepatol. 2018 Sep 28;6(3):317-325. doi: 10.14218/JCTH.2018.00006. Epub 2018 Jul 2.
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Targeting of TAM Receptors Ameliorates Fibrotic Mechanisms in Idiopathic Pulmonary Fibrosis.
Am J Respir Crit Care Med. 2018 Jun 1;197(11):1443-1456. doi: 10.1164/rccm.201707-1519OC.
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Gas6 as a predictor of esophageal varices in patients affected by hepatitis C virus related-chronic liver disease.
Biomark Med. 2018 Jan;12(1):27-34. doi: 10.2217/bmm-2017-0171. Epub 2017 Dec 15.
7
Soluble TAM receptor tyrosine kinases in rheumatoid arthritis: correlation with disease activity and bone destruction.
Clin Exp Immunol. 2018 Apr;192(1):95-103. doi: 10.1111/cei.13082. Epub 2017 Dec 11.
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The non-invasive serum biomarker soluble Axl accurately detects advanced liver fibrosis and cirrhosis.
Cell Death Dis. 2017 Oct 26;8(10):e3135. doi: 10.1038/cddis.2017.554.
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Gas6 as a putative noninvasive biomarker of hepatic fibrosis.
Biomark Med. 2016 Dec;10(12):1241-1249. doi: 10.2217/bmm-2016-0210. Epub 2016 Dec 7.
10
The Gas6/TAM System and Multiple Sclerosis.
Int J Mol Sci. 2016 Oct 28;17(11):1807. doi: 10.3390/ijms17111807.

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