Ghatasheh Ghassan, Al Dhanhani Huda, Goyal Ashutosh, Noureddin Muhammad Bassel, Al Awaad Doaa, Peerwani Ziad
Division of Pediatric Infectious Disease, Tawam Hospital, Al Ain, UAE.
Division of Pediatric Cardialgy, Tawam Hospital, Al Ain, UAE.
Case Rep Infect Dis. 2021 Jan 18;2021:8872412. doi: 10.1155/2021/8872412. eCollection 2021.
Multisystem inflammatory disorder in children and adolescents is a relatively new and rare complication of COVID-19. This complication seems to develop after the infection rather than during the acute phase of COVID-19. The clinical features are similar to a well-known inflammatory syndrome in children, Kawasaki disease, and it can lead to collapse and multiple organ failure requiring intensive care. The COVID-19-associated multisystem inflammatory syndrome in children and adolescents is referred to mutually as pediatric inflammatory multisystem syndrome temporally linked with SARS-CoV-2 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C) correlated with COVID-19, and here, it is referred to as MIS-C. . This report describes a nine-month-old Asian infant presented with a two-week history of fever with nonspecific signs of viral illness and erythematous rash. The clinical and biochemical findings were compatible with complicated typical Kawasaki disease (KD). The infant fulfilled the World Health Organization criteria for MIS-C and was treated with intravenous immunoglobulin and anticoagulation, which he responded well to. He was discharged home in good condition after almost 3 weeks of treatment.
This case highlights a rare but new phenomenon attributed to severe acute respiratory syndrome coronavirus 2 infection. We report the first case report of MIS-C in the United Arab Emirates and Arab region. Among KD's complications, massive aneurysm with thrombosis is rare and usually will have deleterious results if not diagnosed and managed promptly.
儿童和青少年多系统炎症性疾病是新型冠状病毒肺炎（COVID-19）一种相对较新且罕见的并发症。这种并发症似乎在感染后而非COVID-19急性期出现。其临床特征与儿童一种知名的炎症综合征——川崎病相似，并且可导致休克和多器官功能衰竭，需要重症监护。儿童和青少年与COVID-19相关的多系统炎症综合征相互被称为与严重急性呼吸综合征冠状病毒2（SARS-CoV-2）时间相关的儿童炎症性多系统综合征（PIMS-TS）或与COVID-19相关的儿童多系统炎症综合征（MIS-C），在此处称为MIS-C。本报告描述了一名9个月大的亚洲婴儿，有两周发热病史，伴有病毒感染的非特异性体征和红斑皮疹。临床和生化检查结果符合复杂型典型川崎病（KD）。该婴儿符合世界卫生组织MIS-C标准，接受了静脉注射免疫球蛋白和抗凝治疗，反应良好。经过近3周治疗后，他状况良好地出院回家。
本病例突出了一种由严重急性呼吸综合征冠状病毒2感染引起的罕见但新的现象。我们报告了阿拉伯联合酋长国及阿拉伯地区首例MIS-C病例。在KD的并发症中，巨大动脉瘤伴血栓形成罕见，如果不及时诊断和处理，通常会产生有害后果。
