TFT Nano Center, Belgrade, Serbia.
Faculty of Pharmacy, University Business Academy in Novi Sad, Novi Sad, Serbia.
J Cosmet Dermatol. 2021 Sep;20(9):3018-3025. doi: 10.1111/jocd.13965. Epub 2021 Feb 3.
Hyper Harmonized Hydroxyl Modified Fullerene Substance (3HFWC ) establishes hydrogen bonds with the surrounding water molecules and organizes them in clusters with the liquid crystalline state, similar to the properties of water surrounding the biomolecules.
To investigate the moisturizing properties of hyperharmonized fullerenol-3HFWC as an emulsion O/W ingredient on the skin.
PATIENTS/METHODS: We have analyzed the reflexion of the blue light from the skin, in vivo, with different levels of moisturization and compared the influence of three groups of cosmetic products (with various active ingredients, 3HFWC or water in same percentage in the "vehiculum") on skin moisturization by measuring paramagnetic/diamagnetic properties by Optomagnetic Imaging Spectroscopy.
Regenerating Cream and Body Lotion have shown statistically significant increase of diamagnetic features predominantly in all 3 types of creams, while the Hand Cream formulations have not shown statistically significant results after 4 weeks of treatment. Anti-aging cream with 3HFWC demonstrated statistically significant increase of paramagnetic properties of the skin (p /p from 0.90 to 0.62) and showed beneficial effects on information transfer and water content in stratum corneum.
Although it does not act as a classical moisturizing agent on the skin, 3HFWC can increase moisturization as a result of hydrogen bonds established among 3HFWC and water or biomolecules, liquid crystalline state of water in 3HFWC resembling the properties of water surrounding the biomolecules, and finally, liquid crystalline state of water in the products.
超谐和羟基改性富勒烯物质（3HFWC）与周围水分子形成氢键，并将它们组织成具有液晶状态的簇，类似于生物分子周围水的性质。
研究超谐和富勒醇-3HFWC 作为乳液 O/W 成分对皮肤的保湿特性。
患者/方法：我们分析了不同保湿水平下皮肤对蓝光的反射，体内，并比较了三组化妆品（具有不同的活性成分、3HFWC 或相同百分比的水作为“载体”）对皮肤保湿的影响，通过光磁共振成像光谱测量顺磁/抗磁性特性。
再生霜和身体乳液在所有 3 种乳膏中均显示出统计学上显著增加的抗磁性特征，而护手霜配方在治疗 4 周后没有显示出统计学上显著的结果。含有 3HFWC 的抗衰老霜显示皮肤顺磁性质的统计学显著增加（p /p 从 0.90 到 0.62），并对信息传递和角质层中的水分含量具有有益作用。
虽然 3HFWC 本身不是一种经典的皮肤保湿剂，但由于 3HFWC 与水或生物分子之间形成的氢键、3HFWC 中类似于生物分子周围水的性质的水的液晶状态，以及最终产品中形成的水的液晶状态，它可以增加皮肤的保湿效果。
