• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

首例富勒烯衍生物FD-C（富勒醇）与第二例富勒烯衍生物SD-C（3HFWC）的结构及物理化学性质的比较研究

Comparative Studies of the Structural and Physicochemical Properties of the First Fullerene Derivative FD-C (Fullerenol) and Second Fullerene Derivate SD-C (3HFWC).

作者信息

Koruga Djuro, Stanković Ivana, Matija Lidija, Kuhn Dietmar, Christ Bastian, Dembski Sofia, Jevtić Nenad, Janać Jelena, Pavlović Vladimir, De Wever Bart

机构信息

NanoLab, Department of Biomedical Engineering, Faculty of Mechanical Engineering, University of Belgrade, 11220 Belgrade, Serbia.

NanoWorld, 11043 Belgrade, Serbia.

出版信息

Nanomaterials (Basel). 2024 Mar 6;14(5):480. doi: 10.3390/nano14050480.

DOI:10.3390/nano14050480
PMID:38470808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10935211/
Abstract

In order to maximally reduce the toxicity of fullerenol (the first derivative of C, FD-C), and increase its biomedical efficiency, the second derivative SD-C (3HFWC, Hyper-Harmonized Hydroxylated Fullerene Water Complex) was created. Several different methods were applied in the comparative characterization of FD-C and SD-C with the same OH groups in their core. FD-C as an individual structure was about 1.3 nm in size, while SD-C as an individual structure was 10-30 nm in size. Based on ten physicochemical methods and techniques, FD-C and SD-C were found to be two different substances in terms of size, structure, and physicochemical properties; FD-C, at 100 °C, had endothermic characteristics, while SD-C, at 133 °C, had exothermic characteristics; FD-C did not have water layers, while SD-C had water layers; the zeta potential of FD-C was -25.85 mV, while it was -43.29 mV for SD-C. SD-C is a promising substance for use in cosmetics and pharmaceuticals.

摘要

为了最大程度地降低富勒醇（碳的第一代衍生物，FD-C）的毒性，并提高其生物医学效率，人们制备了第二代衍生物SD-C（3HFWC，超协调羟基化富勒烯水络合物）。在对核心具有相同羟基的FD-C和SD-C进行比较表征时，采用了几种不同的方法。FD-C作为单个结构，尺寸约为1.3纳米，而SD-C作为单个结构，尺寸为10-30纳米。基于十种物理化学方法和技术，发现FD-C和SD-C在尺寸、结构和物理化学性质方面是两种不同的物质；FD-C在100°C时具有吸热特性，而SD-C在133°C时具有放热特性；FD-C没有水层，而SD-C有水层；FD-C的zeta电位为-25.85 mV，而SD-C的zeta电位为-43.29 mV。SD-C是一种有前景的用于化妆品和制药的物质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/669a89ebd1c1/nanomaterials-14-00480-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/75716b16c11f/nanomaterials-14-00480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/682182296c80/nanomaterials-14-00480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/7fc860873aaf/nanomaterials-14-00480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/b0f47d652213/nanomaterials-14-00480-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/055cf81c692c/nanomaterials-14-00480-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/7d9296aef32a/nanomaterials-14-00480-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/e25ed6795404/nanomaterials-14-00480-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/9a4cc2bef133/nanomaterials-14-00480-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/c3070c03b9c7/nanomaterials-14-00480-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/cd91fa83e982/nanomaterials-14-00480-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/ac2655ef97b4/nanomaterials-14-00480-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/558d7f2577b7/nanomaterials-14-00480-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/fb363c213efc/nanomaterials-14-00480-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/7f0233f95014/nanomaterials-14-00480-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/e02f1b891c04/nanomaterials-14-00480-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/0a28e778f8ee/nanomaterials-14-00480-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/669a89ebd1c1/nanomaterials-14-00480-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/75716b16c11f/nanomaterials-14-00480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/682182296c80/nanomaterials-14-00480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/7fc860873aaf/nanomaterials-14-00480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/b0f47d652213/nanomaterials-14-00480-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/055cf81c692c/nanomaterials-14-00480-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/7d9296aef32a/nanomaterials-14-00480-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/e25ed6795404/nanomaterials-14-00480-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/9a4cc2bef133/nanomaterials-14-00480-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/c3070c03b9c7/nanomaterials-14-00480-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/cd91fa83e982/nanomaterials-14-00480-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/ac2655ef97b4/nanomaterials-14-00480-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/558d7f2577b7/nanomaterials-14-00480-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/fb363c213efc/nanomaterials-14-00480-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/7f0233f95014/nanomaterials-14-00480-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/e02f1b891c04/nanomaterials-14-00480-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/0a28e778f8ee/nanomaterials-14-00480-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c08/10935211/669a89ebd1c1/nanomaterials-14-00480-g017.jpg

相似文献

1
Comparative Studies of the Structural and Physicochemical Properties of the First Fullerene Derivative FD-C (Fullerenol) and Second Fullerene Derivate SD-C (3HFWC).首例富勒烯衍生物FD-C（富勒醇）与第二例富勒烯衍生物SD-C（3HFWC）的结构及物理化学性质的比较研究
Nanomaterials (Basel). 2024 Mar 6;14(5):480. doi: 10.3390/nano14050480.
2
The Second Derivative of Fullerene C (SD-C) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine.富勒烯C的二阶导数（SD-C）与氢键的生物分子机制：水基纳米医学
Micromachines (Basel). 2023 Nov 25;14(12):2152. doi: 10.3390/mi14122152.
3
Novel C Fullerenol-Gentamicin Conjugate-Physicochemical Characterization and Evaluation of Antibacterial and Cytotoxic Properties.新型 C 富勒醇-庆大霉素缀合物的理化特性表征及抗菌和细胞毒性评价。
Molecules. 2022 Jul 7;27(14):4366. doi: 10.3390/molecules27144366.
4
Melanoma Cell Reprogramming and Awakening of Antitumor Immunity as a Fingerprint of Hyper-Harmonized Hydroxylated Fullerene Water Complex (3HFWC) and Hyperpolarized Light Application .黑色素瘤细胞重编程与抗肿瘤免疫的唤醒作为超协调羟基化富勒烯水络合物（3HFWC）和超极化光应用的特征
Nanomaterials (Basel). 2023 Jan 17;13(3):372. doi: 10.3390/nano13030372.
5
Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance.羟基改性富勒醇物质的皮肤保湿机制。
J Cosmet Dermatol. 2021 Sep;20(9):3018-3025. doi: 10.1111/jocd.13965. Epub 2021 Feb 3.
6
Synthesis of alkyl sulfonated fullerenes without catalyst: improved water solubility by the sulfonate groups.无催化剂合成烷基磺化富勒烯：磺酸基团提高了水溶性。
J Nanosci Nanotechnol. 2011 Nov;11(11):10093-101. doi: 10.1166/jnn.2011.5003.
7
Comparative effects of sulfhydryl compounds on target organellae, nuclei and mitochondria, of hydroxylated fullerene-induced cytotoxicity in isolated rat hepatocytes.巯基化合物对羟基化富勒烯诱导的离体大鼠肝细胞靶细胞器、细胞核及线粒体细胞毒性的比较作用。
J Appl Toxicol. 2015 Dec;35(12):1465-72. doi: 10.1002/jat.3137. Epub 2015 Mar 23.
8
Antioxidant activity of highly hydroxylated fullerene C and its interactions with the analogue of α-tocopherol.高度羟基化富勒烯 C 的抗氧化活性及其与 α-生育酚类似物的相互作用。
Free Radic Biol Med. 2020 Nov 20;160:734-744. doi: 10.1016/j.freeradbiomed.2020.08.017. Epub 2020 Aug 29.
9
Protective role of fullerenol and arginine C fullerene against copper toxicity in cucumber.富勒醇和精氨酸C-富勒烯对黄瓜铜毒性的保护作用。
Plant Physiol Biochem. 2023 Nov;204:108095. doi: 10.1016/j.plaphy.2023.108095. Epub 2023 Oct 16.
10
Anticoronavirus Activity of Water-Soluble Pristine C Fullerenes: In Vitro and In Silico Screenings.水溶性 Pristine C 富勒烯的抗冠状病毒活性：体外和计算机筛选。
Adv Exp Med Biol. 2021;1352:159-172. doi: 10.1007/978-3-030-85109-5_10.

引用本文的文献

1
Molecular "Yin-Yang" Machinery of Synthesis of the Second and Third Fullerene C Derivatives.第二代和第三代富勒烯C衍生物合成的分子“阴阳”机制。
Micromachines (Basel). 2025 Jun 30;16(7):770. doi: 10.3390/mi16070770.
2
Nanofiltration Membranes from Poly(sodium-p-styrenesulfonate)/Polyethylenimine Polyelectrolyte Complex Modified with Carbon Nanoparticles for Enhanced Water Treatment.用于强化水处理的由碳纳米颗粒改性的聚（对苯乙烯磺酸钠）/聚乙烯亚胺聚电解质复合物制备的纳滤膜
Polymers (Basel). 2025 May 10;17(10):1306. doi: 10.3390/polym17101306.

本文引用的文献

1
The Second Derivative of Fullerene C (SD-C) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine.富勒烯C的二阶导数（SD-C）与氢键的生物分子机制：水基纳米医学
Micromachines (Basel). 2023 Nov 25;14(12):2152. doi: 10.3390/mi14122152.
2
A Review of the Current State of Magnetic Force Microscopy to Unravel the Magnetic Properties of Nanomaterials Applied in Biological Systems and Future Directions for Quantum Technologies.磁力显微镜在揭示生物系统中应用的纳米材料磁性特性方面的现状综述及量子技术的未来发展方向
Nanomaterials (Basel). 2023 Sep 18;13(18):2585. doi: 10.3390/nano13182585.
3
The presymptomatic treatment with 3HFWC nanosubstance decreased plaque load in 5XFAD mouse model of Alzheimer's disease.
3HFWC 纳米物质的前驱治疗可减少阿尔茨海默病 5XFAD 小鼠模型中的斑块负担。
CNS Neurosci Ther. 2024 Mar;30(3):e14188. doi: 10.1111/cns.14188. Epub 2023 Mar 27.
4
Melanoma Cell Reprogramming and Awakening of Antitumor Immunity as a Fingerprint of Hyper-Harmonized Hydroxylated Fullerene Water Complex (3HFWC) and Hyperpolarized Light Application .黑色素瘤细胞重编程与抗肿瘤免疫的唤醒作为超协调羟基化富勒烯水络合物（3HFWC）和超极化光应用的特征
Nanomaterials (Basel). 2023 Jan 17;13(3):372. doi: 10.3390/nano13030372.
5
Physiological Response, Oxidative Stress Assessment and Aquaporin Genes Expression of Cherry Tomato ( L.) Exposed to Hyper-Harmonized Fullerene Water Complex.暴露于超调和富勒烯水复合物的樱桃番茄（L.）的生理反应、氧化应激评估及水通道蛋白基因表达
Plants (Basel). 2022 Oct 22;11(21):2810. doi: 10.3390/plants11212810.
6
Combined Action of Hyper-Harmonized Hydroxylated Fullerene Water Complex and Hyperpolarized Light Leads to Melanoma Cell Reprogramming In Vitro.超协调羟基化富勒烯水络合物与超极化光的联合作用导致黑色素瘤细胞在体外重编程。
Nanomaterials (Basel). 2022 Apr 13;12(8):1331. doi: 10.3390/nano12081331.
7
Investigation of Red Blood Cells by Atomic Force Microscopy.原子力显微镜观察红细胞。
Sensors (Basel). 2022 Mar 7;22(5):2055. doi: 10.3390/s22052055.
8
Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance.羟基改性富勒醇物质的皮肤保湿机制。
J Cosmet Dermatol. 2021 Sep;20(9):3018-3025. doi: 10.1111/jocd.13965. Epub 2021 Feb 3.
9
Developing [60]Fullerene Nanomaterials for Better Photodynamic Treatment of Non-Melanoma Skin Cancers.开发[60]富勒烯纳米材料以更好地进行非黑色素瘤皮肤癌的光动力治疗。
ACS Biomater Sci Eng. 2020 Oct 12;6(10):5930-5940. doi: 10.1021/acsbiomaterials.0c00932. Epub 2020 Sep 11.
10
Influence of hyper-harmonized fullerene water complex on collagen quality and skin function.超调和富勒烯水合物复合物对胶原蛋白质量和皮肤功能的影响。
J Cosmet Dermatol. 2020 Feb;19(2):494-501. doi: 10.1111/jocd.12999. Epub 2019 May 29.