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Explore structural and functional brain changes in insomnia disorder: A PRISMA-compliant whole brain ALE meta-analysis for multimodal MRI.探索失眠症患者大脑的结构和功能变化：一项符合PRISMA标准的多模态MRI全脑ALE荟萃分析。
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Multimodal Abnormalities of Brain Structure and Function in Major Depressive Disorder: A Meta-Analysis of Neuroimaging Studies.重性抑郁障碍的脑结构和功能的多模态异常：神经影像学研究的荟萃分析。
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Co-Morbid Insomnia and Sleep Apnea (COMISA): Prevalence, Consequences, Methodological Considerations, and Recent Randomized Controlled Trials.共病性失眠与睡眠呼吸暂停（COMISA）：患病率、后果、方法学考量及近期随机对照试验
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Neuroimaging insights into the link between depression and Insomnia: A systematic review.神经影像学对抑郁症与失眠之间关联的研究进展：系统综述。
J Affect Disord. 2019 Nov 1;258:133-143. doi: 10.1016/j.jad.2019.07.089. Epub 2019 Jul 31.
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Worldwide and regional prevalence rates of co-occurrence of insomnia and insomnia symptoms with obstructive sleep apnea: A systematic review and meta-analysis.全球及各地区共病失眠及失眠症状与阻塞性睡眠呼吸暂停的患病率：系统回顾和荟萃分析。
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Structural and functional brain alterations in obstructive sleep apnea: a multimodal meta-analysis.阻塞性睡眠呼吸暂停的结构和功能脑改变：多模态荟萃分析。
Sleep Med. 2019 Feb;54:195-204. doi: 10.1016/j.sleep.2018.09.025. Epub 2018 Oct 28.
7
Association of Anxiety and Depression in Obstructive Sleep Apnea Patients: A Systematic Review and Meta-Analysis.阻塞性睡眠呼吸暂停患者的焦虑和抑郁相关性：系统评价和荟萃分析。
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Depression.抑郁。
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9
Obstructive sleep apnea and the metabolic syndrome: The road to clinically-meaningful phenotyping, improved prognosis, and personalized treatment.阻塞性睡眠呼吸暂停与代谢综合征：通向有临床意义的表型分析、改善预后和个体化治疗的道路。
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10
Polysomnography for Obstructive Sleep Apnea Should Include Arousal-Based Scoring: An American Academy of Sleep Medicine Position Statement.阻塞性睡眠呼吸暂停的多导睡眠图检查应包括基于觉醒的评分：美国睡眠医学学会立场声明。
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共病阻塞性睡眠呼吸暂停和失眠中的抑郁症状：一项综合综述。

Depressive Symptoms in Comorbid Obstructive Sleep Apnea and Insomnia: An Integrative Review.

作者信息

Jeon Bomin, Luyster Faith S, Callan Judith A, Chasens Eileen R

机构信息

School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.

出版信息

West J Nurs Res. 2021 Feb 3:193945921989656. doi: 10.1177/0193945921989656.

DOI:10.1177/0193945921989656
PMID:33533324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8329133/
Abstract

The purpose of this integrative review was to synthesize evidence concerning the relationship between comorbid obstructive sleep apnea and insomnia (OSA+I), and depressive symptoms. OSA and insomnia are common sleep disorders, recently comorbid OSA+I has been recognized as prevalent in adults. Although each sleep disorder increases the risk and severity of depressive symptoms, the effect of comorbid OSA+I on depressive symptoms remains unclear. A systematic search of PubMed, CINAHL, and PsycINFO identified 15 data-based studies. All the studies were observational with either a cross-sectional (n = 14) or a case-control design (n = 1). Study quality was assessed. Most of the studies (n = 14) indicated that comorbid OSA+I had an additive role on depressive symptoms. Insomnia appeared to have a more important role than OSA in increasing the severity of depressive symptoms in persons with comorbid OSA+I.

摘要

本综合性综述的目的是综合有关阻塞性睡眠呼吸暂停合并失眠（OSA+I）与抑郁症状之间关系的证据。阻塞性睡眠呼吸暂停（OSA）和失眠是常见的睡眠障碍，最近OSA+I在成年人中被认为很普遍。尽管每种睡眠障碍都会增加抑郁症状的风险和严重程度，但OSA+I合并症对抑郁症状的影响仍不明确。通过对PubMed、CINAHL和PsycINFO进行系统检索，确定了15项基于数据的研究。所有研究均为观察性研究，采用横断面设计（n = 14）或病例对照设计（n = 1）。对研究质量进行了评估。大多数研究（n = 14）表明，OSA+I合并症对抑郁症状具有累加作用。在OSA+I合并症患者中，失眠在增加抑郁症状严重程度方面似乎比OSA起着更重要的作用。