Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada.
Prevention and Early Intervention Programme for Psychosis (PEPP-Montreal), Douglas Mental Health University Institute, 7070 boul. Champlain, Verdun, Montreal, QC, H4H 1A8, Canada.
Curr Psychiatry Rep. 2021 Feb 3;23(3):11. doi: 10.1007/s11920-021-01224-0.
We summarize the history of the clinical high-risk stage of psychosis (CHR), current research on this stage and recent critiques of the field, and evaluate current CHR guidelines and frameworks.
Following its identification and characterization, CHR services have successfully been developed in North America, Europe, Australia and elsewhere. As reflected in guidelines, these services and their orientation largely emerged as an outgrowth of the framework pioneered by early intervention services for first-episode psychosis. We critically discuss what is known so far about the subjective experience of the CHR syndrome, the meaning of this "unofficial" diagnosis as well as what is known and unknown about the service-related needs. While a range of outstanding questions remain in the field, there is a particular need for patient-oriented work and to investigate the service-related needs of young people at CHR.
总结精神分裂症高危期(CHR)的临床阶段的历史,目前对该阶段的研究以及该领域的最新批评,并评估当前的 CHR 指南和框架。
在确定和描述该阶段后,CHR 服务已在北美、欧洲、澳大利亚和其他地区成功开发。正如指南所反映的那样,这些服务及其定位主要是早期干预首发精神病服务所开创的框架的产物。我们批判性地讨论了目前对 CHR 综合征主观体验的了解,对这一“非正式”诊断的意义,以及对与服务相关的需求的了解和未知。虽然该领域仍存在一系列悬而未决的问题,但特别需要进行以患者为中心的工作,并调查 CHR 年轻人的服务相关需求。