Department of Affective and Psychotic Disorders, Medical University of Lodz, Lodz, Poland.
Department of Diagnostic Imaging, Polish Mother's Memorial Hospital-Research Institute, Lodz, Poland.
Early Interv Psychiatry. 2020 Dec;14(6):741-750. doi: 10.1111/eip.12950. Epub 2020 Feb 17.
Clinical research into the Clinical High Risk state for Psychosis (CHR-P) has allowed primary indicated prevention in psychiatry to improve outcomes of psychotic disorders. The strategic component of this approach is the implementation of clinical services to detect and take care of CHR-P individuals, which are recommended by several guidelines. The actual level of implementation of CHR-P services worldwide is not completely clear.
To assess the global geographical distribution, core characteristics relating to the level of implementation of CHR-P services; to overview of the main barriers that limit their implementation at scale.
CHR-P services worldwide were invited to complete an online survey. The survey addressed the geographical distribution, general implementation characteristics and implementation barriers.
The survey was completed by 47 CHR-P services offering care to 22 248 CHR-P individuals: Western Europe (51.1%), North America (17.0%), East Asia (17.0%), Australia (6.4%), South America (6.4%) and Africa (2.1%). Their implementation characteristics included heterogeneous clinical settings, assessment instruments and length of care offered. Most CHR-P patients were recruited through mental or physical health services. Preventive interventions included clinical monitoring and crisis management (80.1%), supportive therapy (70.2%) or structured psychotherapy (61.7%), in combination with pharmacological treatment (in 74.5%). Core implementation barriers were staffing and financial constraints, and the recruitment of CHR-P individuals. The dynamic map of CHR-P services has been implemented on the IEPA website: https://iepa.org.au/list-a-service/.
Worldwide primary indicated prevention of psychosis in CHR-P individuals is possible, but the implementation of CHR-P services is heterogeneous and constrained by pragmatic challenges.
对精神病高危状态(CHR-P)的临床研究使得精神医学中可以进行初级的有指向性预防,以改善精神病性障碍的结局。该方法的战略组成部分是实施临床服务,以发现和照顾 CHR-P 个体,这已被多项指南所推荐。但目前全球 CHR-P 服务的实际实施水平尚不完全清楚。
评估全球地理分布,与 CHR-P 服务实施水平相关的核心特征;概述限制其大规模实施的主要障碍。
邀请全球的 CHR-P 服务机构完成一项在线调查。该调查涉及地理分布、一般实施特征和实施障碍。
该调查由 47 家为 CHR-P 个体提供服务的 CHR-P 服务机构完成,共照护了 22248 名 CHR-P 个体:西欧(51.1%)、北美(17.0%)、东亚(17.0%)、澳大利亚(6.4%)、南美(6.4%)和非洲(2.1%)。其实施特征包括不同的临床环境、评估工具和提供的护理时长。大多数 CHR-P 患者通过精神或身体健康服务招募。预防干预措施包括临床监测和危机管理(80.1%)、支持性治疗(70.2%)或结构化心理治疗(61.7%),同时结合药物治疗(74.5%)。核心实施障碍是人员配备和财务限制,以及 CHR-P 个体的招募。CHR-P 服务的动态地图已在 IEPA 网站上实施:https://iepa.org.au/list-a-service/。
在 CHR-P 个体中进行全球初级有指向性预防精神病是可能的,但 CHR-P 服务的实施存在异质性,并受到实际挑战的限制。