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科威特人类布鲁氏菌病的特征:379例病例研究

The nature of human brucellosis in Kuwait: study of 379 cases.

作者信息

Mousa A R, Elhag K M, Khogali M, Marafie A A

机构信息

Department of Medicine, Al Adan Hospital, Safat, Kuwait.

出版信息

Rev Infect Dis. 1988 Jan-Feb;10(1):211-7. doi: 10.1093/clinids/10.1.211.

DOI:10.1093/clinids/10.1.211
PMID:3353631
Abstract

Three hundred seventy-nine Kuwaiti patients with brucellosis were admitted to Adan General Hospital, Kuwait, during the period 1984-1985. Of these 231 were males and 148 were females. Diagnosis was based on symptoms and signs compatible with the disease and on the detection of significantly elevated antibody titer and/or positive blood culture. The primary means of exposure were the consumption of raw milk and contact with goats, sheep, or camels. Patients most frequently presented with fever (91%), chills (40%), sweats (39%), gastrointestinal symptoms (30%), headache (23%), respiratory symptoms (23%), and musculoskeletal symptoms (22%). The major signs were osteoarticular involvement (37%), hepatosplenomegaly (27%), and lymphadenopathy (9%). Different regimens of treatment were used, but the highest rate of cure was achieved with triple therapy--tetracycline, streptomycin, and rifampin.

摘要

1984年至1985年期间,379名科威特布鲁氏菌病患者被收治于科威特阿丹综合医院。其中男性231名,女性148名。诊断依据为与该病相符的症状和体征,以及检测到显著升高的抗体滴度和/或血培养呈阳性。主要接触途径是饮用生奶以及接触山羊、绵羊或骆驼。患者最常出现的症状为发热(91%)、寒战(40%)、盗汗(39%)、胃肠道症状(30%)、头痛(23%)、呼吸道症状(23%)和肌肉骨骼症状(22%)。主要体征为骨关节受累(37%)、肝脾肿大(27%)和淋巴结病(9%)。采用了不同的治疗方案,但三联疗法(四环素、链霉素和利福平)的治愈率最高。

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