Sabzevari Nina, Qiblawi Sultan, Norton Scott A, Fivenson David
St. Joseph Mercy Hospital, Dermatology Resident, 5333 McAuley Drive, Suite 5003, Ypsilanti, MI 48197, USA.
Michigan State University College of Human Medicine, 965 Fee Rd A110, East Lansing, MI 48824, USA.
Int J Womens Dermatol. 2021 Jan 23;7(1):28-44. doi: 10.1016/j.ijwd.2020.05.017. eCollection 2021 Jan.
Sunscreens are topical preparations containing any number of ultraviolet filters (UVFs). The first part of the review will focus on the recent Food and Drug Administration (FDA) regulations of 2019 and general use of these agents. While sunscreen products are becoming more regulated in the United States, we still lag behind other countries in our options for UVFs. Sun protection to prevent skin cancer and aging changes should be a combination of sun avoidance, protective structures, and clothing as well as use of sunscreen products. Newer and safer products are needed to help supplement and replace older agents as well as improve their cosmetic acceptability. This will be a review of ingredients, local toxicities (i.e. contact dermatitis, photocontact dermatitis), special considerations for children, and cosmesis of sunscreen preparations. Part 2 will focus on the environmental, ecological and human toxicities that have been increasingly related to UVFs.
防晒霜是含有多种紫外线过滤剂(UVF)的局部用制剂。综述的第一部分将聚焦于2019年美国食品药品监督管理局(FDA)的最新规定以及这些制剂的一般用途。虽然美国对防晒产品的监管日益严格,但在紫外线过滤剂的选择方面,我们仍落后于其他国家。预防皮肤癌和衰老变化的防晒措施应包括避免日晒、使用防护设施和穿着衣物,以及使用防晒产品。需要更新、更安全的产品来补充和替代旧产品,并提高其在美容方面的可接受性。本文将对防晒制剂的成分、局部毒性(如接触性皮炎、光接触性皮炎)、儿童的特殊注意事项以及美容效果进行综述。第二部分将聚焦于与紫外线过滤剂日益相关的环境、生态和人体毒性。