P. Stirling, L. Strom, M. Saffarini, L. Nover, ReSurg SA, Nyon, Switzerland.
P. Stirling, ReSurg UK, Herefordshire, UK.
Clin Orthop Relat Res. 2021 May 1;479(5):1119-1130. doi: 10.1097/CORR.0000000000001618.
One goal of THA is to restore the anatomic hip center, which can be achieved in hips with developmental dysplasia by placing cups at the level of the native acetabulum. However, this might require adjuvant procedures such as femoral shortening osteotomy. Another option is to place the cup at the high hip center, potentially reducing surgical complexity. Currently, no clear consensus exists regarding which of these cup positions might offer better functional outcomes or long-term survival.
QUESTION/PURPOSE: We performed a systematic review to determine whether (1) functional outcomes as measured by the Harris hip score, (2) revision incidence, and (3) complications that do not result in revision differ based on the position of the acetabular cup (high hip center versus anatomic hip center) in patients undergoing THA for developmental dysplasia of the hip (DDH).
We performed a systematic review using Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, including studies comparing the functional outcomes, revision incidence, and complications of primary THA in dysplastic hips with acetabular cups placed at the high hip center versus those placed at the anatomic hip center, over any time frame. The review protocol was registered with PROSPERO (registration number CRD42020168183) before commencement. Of 238 records, eight comparative, retrospective nonrandomized studies of interventions were eligible for our systematic review, reporting on 207 hips with cups placed at the high hip center and 268 hips with cups at the anatomic hip center. Risk of bias within eligible studies was assessed using the Risk Of Bias In Non-randomized Studies of Interventions tool. Due to low comparability between studies, data could not be pooled, so these studies were assessed without summary effects.
Six studies compared Harris hip scores, two of which favored high hip center cup placement and three of which favored anatomic hip center cup placement, although none of the differences between cohorts met the minimum clinically important difference. Five studies reliably compared revision incidence, which ranged from 2% to 9% for high hip center at 7 to 15 years and 0% to 5.9% for anatomic hip center at 6 to 16 years. Five studies reported intra- and postoperative complications, with the high hip center being associated with higher incidence of dislocation and lower incidence of neurological complications. No clear difference was observed in intraoperative complications between the high hip center and anatomic hip center.
No obvious differences could be observed in Harris hip score or revision incidence after THA for osteoarthritis secondary to DDH between cups placed at the anatomic hip center and those placed at the high hip center. Placement of the acetabular cup in the high hip center may lead to higher risk of dislocation but lower risk of neurologic complications, although no difference in intraoperative complications was observed. Surgeons should be able to achieve satisfactory functional scores and revision incidence using either technique, although they should be aware of how their choice influences hip biomechanics and the need for adjunct procedures and associated risks and operative time. These recommendations should be considered with respect to the several limitations in the studies reviewed, including the presence of serious confounding factors and selection biases, inconsistent definitions of the high hip center, variations in dysplasia severity, small sample sizes, and follow-up periods. These weaknesses should be addressed in well-designed future studies.
Level III, therapeutic study.
全髋关节置换术(THA)的目标之一是恢复解剖学髋关节中心,对于发育性髋关节发育不良的髋关节,可以通过将髋臼杯置于原生髋臼水平来实现。然而,这可能需要辅助手术,如股骨短缩截骨术。另一种选择是将髋臼杯置于高髋关节中心,从而可能降低手术复杂性。目前,对于哪种髋臼杯位置可能提供更好的功能结果或长期生存率,尚无明确共识。
问题/目的:我们进行了一项系统评价,以确定在发育性髋关节发育不良(DDH)患者中进行 THA 时,髋臼杯位置(高髋关节中心与解剖学髋关节中心)是否会影响(1)Harris 髋关节评分测量的功能结果,(2)翻修发生率,以及(3)不会导致翻修的并发症。
我们使用系统评价的 Preferred Reporting Items for Systematic Reviews and Meta-analysis(PRISMA)指南进行了一项系统评价,包括比较髋臼杯置于高髋关节中心与置于解剖学髋关节中心的原发性 THA 在发育性髋关节不良患者中的功能结果、翻修发生率和并发症的研究,时间范围不限。在开始前,我们使用 PROSPERO(注册号 CRD42020168183)注册了审查方案。在 238 条记录中,有 8 项比较干预措施的回顾性非随机对照研究符合我们的系统评价标准,共报告了 207 髋髋臼杯置于高髋关节中心和 268 髋髋臼杯置于解剖学髋关节中心。使用非随机干预措施风险评估工具评估合格研究中的偏倚风险。由于研究之间可比性低,无法进行数据汇总,因此对这些研究进行了无综合效应的评估。
有 6 项研究比较了 Harris 髋关节评分,其中 2 项研究支持高髋关节中心杯放置,3 项研究支持解剖学髋关节中心杯放置,但两组之间的任何差异均未达到最小临床重要差异。有 5 项研究可靠地比较了翻修发生率,高髋关节中心髋臼杯的翻修发生率为 7 至 15 年时为 2%至 9%,解剖学髋关节中心髋臼杯的翻修发生率为 6 至 16 年时为 0%至 5.9%。有 5 项研究报告了术中及术后并发症,高髋关节中心与更高的脱位发生率相关,而与较低的神经并发症发生率相关。在高髋关节中心和解剖学髋关节中心之间,未观察到术中并发症的明显差异。
在 DDH 继发骨关节炎的 THA 后,髋臼杯置于解剖学髋关节中心与置于高髋关节中心之间,Harris 髋关节评分或翻修发生率无明显差异。髋臼杯置于高髋关节中心可能导致更高的脱位风险,但神经并发症风险较低,尽管术中并发症无差异。外科医生可以使用这两种技术获得满意的功能评分和翻修发生率,但应注意其选择如何影响髋关节生物力学以及辅助手术的必要性及其相关风险和手术时间。应考虑到所审查研究中的几个局限性,包括严重混杂因素和选择偏倚的存在、高髋关节中心定义不一致、发育不良严重程度的变化、样本量小以及随访时间。这些弱点应在未来的设计良好的研究中得到解决。
III 级,治疗性研究。