Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Centre for Contemporary Fiqh and Sharia Compliance, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Hum Vaccin Immunother. 2021 Jul 3;17(7):2158-2168. doi: 10.1080/21645515.2020.1865044. Epub 2021 Feb 4.
Influenza virus is a life-threatening pathogen that infects millions of people every year, with annual mortality in the hundreds of thousands. The scenario for controlling infection has worsened with increasing numbers of vaccine hesitancy cases reported worldwide due to objections on safety, religious and other grounds. Uses of (impermissible) and (doubtful) ingredients in vaccine production has raised doubts among Muslim consumers and consequently stimulated serious vaccine hesitancy. To address this major problem, we have reviewed and recommended some alternatives appropriate for manufacturing cell-based influenza vaccine which comply with Islamic laws and consumers' needs. Intensive assessments of current influenza vaccine production in both scientific and Islamic views have led to the identification of four main ingredients deemed impermissible in novel sharia-compliant (approved by Islamic laws) vaccine manufacturing. Only some of these impermissible components could be replaced with (permissible) alternatives, while others remain impermissible due to unavailability and unsuitability.
流感病毒是一种危及生命的病原体，每年感染数百万人，每年有数十万人因此死亡。由于安全性、宗教和其他原因的反对，全球报告的疫苗犹豫病例越来越多，控制感染的情况恶化了。疫苗生产中使用（不允许的）和（可疑的）成分引起了穆斯林消费者的质疑，因此导致了严重的疫苗犹豫。为了解决这个主要问题，我们已经审查并推荐了一些适合制造基于细胞的流感疫苗的替代品，这些替代品符合伊斯兰教法律和消费者的需求。从科学和伊斯兰教的角度对当前流感疫苗生产进行了深入评估，确定了在新型符合伊斯兰教教法的（伊斯兰教法律批准的）疫苗生产中被认为不允许的四种主要成分。只有其中一些不允许的成分可以用（允许的）替代品替代，而其他成分由于不可用和不适用而仍然不允许。
