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影响普通人群抗生素使用的因素:西班牙的一项定性研究。

Factors determining antibiotic use in the general population: A qualitative study in Spain.

机构信息

Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, A Coruña (Corunna), Spain.

University Hospital of Santiago de Compostela, Santiago de Compostela, A Coruña (Corunna), Spain.

出版信息

PLoS One. 2021 Feb 4;16(2):e0246506. doi: 10.1371/journal.pone.0246506. eCollection 2021.

Abstract

BACKGROUND

Antibiotic resistance is an important Public Health problem and many studies link it to antibiotic misuse. The population plays a key role in such misuse.

OBJECTIVE

The aim of this study was thus to explore the factors that might influence antibiotic use and resistance in the general population.

METHODS

Qualitative research using the focus group (FG) method. Groups were formed by reference to the following criteria: age (over and under 65 years); place of origin; and educational/professional qualifications. FG sessions were recorded, transcribed and then separately analysed by two researchers working independently. Written informed consent was obtained from all participants.

RESULTS

Eleven FGs were formed with a total of 75 participants. The principal factors identified as possible determinants of antibiotic misuse were: (i) lack of knowledge about antibiotics; (ii) doctor-patient relationship problems; (iii) problems of adherence; and, (iv) use without medical prescription. Antibiotic resistance is a phenomenon unknown to the population and is perceived as an individual problem, with the term "resistance" being confused with "tolerance". None of the groups reported that information about resistance had been disseminated by the health care sector.

CONCLUSIONS

The public is unaware of the important role it plays in the advance of antimicrobial resistance. There is evidence of diverse factors, many of them modifiable, which might account for antibiotic misuse. Better understanding these factors could be useful in drawing up specific strategies aimed at improving antibiotic use.

摘要

背景

抗生素耐药性是一个重要的公共卫生问题,许多研究将其与抗生素滥用联系起来。人群在这种滥用中起着关键作用。

目的

本研究旨在探讨可能影响普通人群抗生素使用和耐药性的因素。

方法

采用焦点小组(FG)方法进行定性研究。根据以下标准形成小组:年龄(65 岁以上和 65 岁以下);原籍地;和教育/专业资格。FG 会议被记录、转录,然后由两名独立工作的研究人员分别进行分析。所有参与者均获得书面知情同意。

结果

共形成了 11 个 FG,共有 75 名参与者。确定为抗生素滥用可能决定因素的主要因素有:(i)缺乏抗生素知识;(ii)医患关系问题;(iii)用药依从性问题;以及,(iv)未经处方使用抗生素。人群对抗生素耐药性现象一无所知,并且将其视为个体问题,将“耐药性”一词与“耐受性”混淆。没有一个小组报告说卫生保健部门已经传播了有关耐药性的信息。

结论

公众不知道自己在推进抗微生物药物耐药性方面所扮演的重要角色。有证据表明存在多种因素,其中许多是可以改变的,这些因素可能导致抗生素滥用。更好地了解这些因素可能有助于制定旨在改善抗生素使用的具体策略。

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