University of Southern Denmark, Campussvej 55, Odense, Denmark.
Lawrence Berkley National Laboratories, Cyclotron Rd. 1, Berkeley, CA, United States.
Curr Opin Biotechnol. 2021 Feb;67:119-129. doi: 10.1016/j.copbio.2021.01.014. Epub 2021 Feb 2.
Favorable interspecies associations prevail in natural microbial assemblages. Some of these favorable associations are co-metabolic dependent partnerships in which extracellular electrons are exchanged between species. For such electron exchange to occur, the cells must exhibit electroactive interfaces and get involved in direct cell-to-cell contact (Direct Interspecies Electron Transfer/DIET) or use available conductive mineral grains from their environment (Conductive-particle-mediated Interspecies Electron Transfer/CIET). This review will highlight recent discoveries and knowledge gaps regarding DIET and CIET interspecies associations in artificial co-cultures and consortia from natural and man-made environments and emphasize approaches to validate DIET and CIET. Additionally, we acknowledge the initiation of a movement towards applying electric syntrophies in biotechnology, bioremediation and geoengineering for natural attenuation of toxic compounds. Next, we have highlighted the urgent research needs that must be met to develop such technologies.
在自然微生物群落中，有利的种间相互作用占主导地位。其中一些有利的相互作用是共代谢依赖的伙伴关系，其中细胞间交换细胞外电子。为了发生这种电子交换，细胞必须表现出电活性界面并直接参与细胞间接触（直接种间电子转移/DIET）或利用环境中可用的导电矿物颗粒（导电颗粒介导的种间电子转移/CIET）。本综述将重点介绍最近在自然和人为环境中的人工共培养物和联合体中有关 DIET 和 CIET 种间相互作用的发现和知识空白，并强调验证 DIET 和 CIET 的方法。此外，我们承认在生物技术、生物修复和地质工程中应用电动共生体以实现有毒化合物的自然衰减的趋势。接下来，我们强调了必须满足的紧急研究需求，以开发此类技术。
