State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou, China.
Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Crit Rev Biotechnol. 2021 May;41(3):317-338. doi: 10.1080/07388551.2020.1853032. Epub 2021 Mar 17.
The application of microbial strains as axenic cultures has frequently been employed in a diverse range of sectors. In the natural environment, microbes exist as multispecies and perform better than monocultures. Cell signaling and communication pathways play a key role in engineering microbial consortia, because in a consortium, the microorganisms communicate diffusible signal molecules. Mixed microbial cultures have gained little attention due to the lack of proper knowledge about their interactions with each other. Some ideas have been proposed to deal with and study various microbes when they live together as a community, for biotechnological application purposes. In natural environments, microbes can possess unique metabolic features. Therefore, microbial consortia divide the metabolic burden among strains in the group and robustly perform pesticide degradation. Synthetic microbial consortia can perform the desired functions at naturally contaminated sites. Therefore, in this article, special attention is paid to the microbial consortia and their function in the natural environment. This review comprehensively discusses the recent applications of microbial consortia in pesticide degradation and environmental bioremediation. Moreover, the future directions of synthetic consortia have been explored. The review also explores the future perspectives and new platforms for these approaches, besides highlighting the practical understanding of the scientific information behind consortia.
微生物菌株作为无菌培养物的应用在许多领域都得到了广泛应用。在自然环境中,微生物以多物种形式存在,其表现优于单培养物。细胞信号转导和通讯途径在工程微生物群落中起着关键作用,因为在群落中,微生物通过可扩散信号分子进行通讯。由于缺乏对微生物相互作用的适当了解,混合微生物培养物的关注度较低。为了实现生物技术应用的目的,已经提出了一些处理和研究各种微生物共同生活的方法。在自然环境中,微生物可以具有独特的代谢特征。因此,微生物群落将代谢负担在群体中的菌株之间进行分配,并有效地进行农药降解。合成微生物群落可以在自然污染的地点执行所需的功能。因此,本文特别关注微生物群落及其在自然环境中的功能。本文全面讨论了微生物群落在农药降解和环境生物修复中的最新应用。此外,还探讨了合成群落的未来方向。该综述还探讨了这些方法的未来前景和新平台,同时强调了对群落背后科学信息的实际理解。