Jia Yisong, Lv Siying, Bai Shangjie
Department of Otorhinolaryngology Head and Neck Surgery，Yanbian University Affiliated Hospital Organzation，Yanji，133000，China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Jan 5;35(1):34-37. doi: 10.13201/j.issn.2096-7993.2021.01.008.
To investigate the olfactory function of patients with obstructive sleep apnea（OSA） without any treatment, and to providereference for clinical olfactory research. One hundred and thirty-one participants underwent polysomnography（PSG） overnight, and were divided into OSA group （observation group） and non-OSA group （control group） according to the results. The two groups were examined by the Korean version of the olfactory stick test Ⅱ（Korean Bersion） of Sniffin Sticks Test （KVSS Test Ⅱ）. SPSS 26.0 statistical software were used to analyze the data. There was a significant difference in the incidence of olfactory disorders between the observation group and the control group（²=12.000, =0.001）. The rate of olfactory disorders in patients with severe OSA was significantly higher than that in patients with mild OSA（<0.05）, and the proportion of patients with olfactory disorders increased with the increase of OSA severity（²=10.672, =0.001）. There was no statistically significant difference between the observation group and the control group in the severity of olfactory disorders（hyposmia and anosmia）（=1.000）. KVSS between two groups of Test Ⅱ total score has no statistical difference（=1.166, =0.249）, the sense of smell recognition scores also has no statistical difference（=1.598, =0.116）, but the olfactory threshold score and olfactory cognition scores were statistically significant（=5.346, =6.405, <0.001）. OSA has a negative effect on the sense of smell, and the severity of OSA is positively correlated with the incidence of olfactory disorder. OSA olfactory disorder is mainly anosmia, and the main manifestation is the decrease of olfactory cognitive scores.
探讨未经任何治疗的阻塞性睡眠呼吸暂停（OSA）患者的嗅觉功能，为临床嗅觉研究提供参考。131名参与者接受了整夜多导睡眠图（PSG）检查，并根据结果分为OSA组（观察组）和非OSA组（对照组）。两组均采用嗅觉棒测试Ⅱ的韩语版（韩国版）进行检查。使用SPSS 26.0统计软件分析数据。观察组与对照组嗅觉障碍发生率差异有统计学意义（²=12.000，=0.001）。重度OSA患者嗅觉障碍发生率显著高于轻度OSA患者（<0.05），且嗅觉障碍患者比例随OSA严重程度增加而升高（²=10.672，=0.001）。观察组与对照组嗅觉障碍（嗅觉减退和嗅觉丧失）严重程度差异无统计学意义（=1.000）。两组间嗅觉棒测试Ⅱ总分无统计学差异（=1.166，=0.249），嗅觉识别得分也无统计学差异（=1.598，=0.116），但嗅觉阈值得分和嗅觉认知得分差异有统计学意义（=5.346，=6.405，<0.001）。OSA对嗅觉有负面影响，OSA严重程度与嗅觉障碍发生率呈正相关。OSA嗅觉障碍主要为嗅觉丧失，主要表现为嗅觉认知得分降低。
