Johns Hopkins University, School of Medicine, Department of Anesthesiology and Critical Care Medicine, Baltimore, MD, USA.
Department of Anesthesiology Yale School of Medicine, Division of Applied Hemodynamics, New Haven, CT, USA.
Clin Chest Med. 2021 Mar;42(1):133-141. doi: 10.1016/j.ccm.2020.11.013. Epub 2021 Jan 8.
The incidence of pulmonary hypertension (PH) in patients undergoing noncardiac surgery has increased steadily over the past decade. Patients with known PH have significantly higher perioperative morbidity and mortality than those without PH. Moreover, a substantial number of patients may have occult disease. It, therefore, is of paramount importance for perioperative providers to recognize high-risk patients and treat them appropriately. This review first provides an overview of PH pathophysiology, then estimates the perioperative incidence of PH and its impact on surgical outcomes, and finally outlines a perioperative management strategy.
在过去的十年中,接受非心脏手术的患者中肺动脉高压(PH)的发病率稳步上升。患有已知 PH 的患者在围手术期的发病率和死亡率明显高于没有 PH 的患者。此外,相当数量的患者可能患有隐匿性疾病。因此,围手术期提供者识别高危患者并进行适当治疗至关重要。本综述首先概述了 PH 的病理生理学,然后估计了 PH 的围手术期发生率及其对手术结果的影响,最后概述了围手术期管理策略。