Department of Internal Medicine, College of Medicine, Prince Sattam bin Abdulaziz University, Al-kharj, Saudi Arabia
Department of Cardiology, CHU-Toulouse, University Hospital of Toulouse, Hôpital Rangueil, Toulouse, France.
BMJ Case Rep. 2021 Feb 4;14(2):e236784. doi: 10.1136/bcr-2020-236784.
Platypnoea-orthodeoxia syndrome (POS) is defined by oxygen desaturation and dyspnoea in upright position that improves by lying down. It results from a right to left shunt at the intracardiac or intrapulmonary level. A 53-year-old ovarian cancer patient presented with POS that was refractory to oxygen therapy. The symptoms began after an extensive abdominal and pelvic surgery as treatment of her cancer with a complex hospital course. A patent foramen ovale was found with the use of transoesophageal echocardiography. A percutaneous closure was done with positive outcome and dyspnoea disappearance. In this case with its challenging clinical setting, we present a unique clinical scenario of an immediate postoperative POS syndrome. We address the different therapeutic modalities and the need for a multidisciplinary medical approach.
并氧合-低氧血症（POS）综合征的定义为患者在直立位时发生氧饱和度下降和呼吸困难，而在躺下时得到改善。它是由心内或肺内的右向左分流引起的。一名 53 岁的卵巢癌患者出现 POS，对氧疗有反应。该症状是在广泛的腹部和骨盆手术后开始出现的，这是对她的癌症进行治疗的一部分，且伴随复杂的住院过程。经食管超声心动图发现卵圆孔未闭。经皮闭合术取得了阳性结果，呼吸困难消失。在这种具有挑战性的临床环境下，我们呈现了一个独特的术后即刻 POS 综合征的临床病例。我们讨论了不同的治疗方式，以及对多学科医疗方法的需求。
