ARDEC Academy, viale Giovanni Pascoli, 67 47923, Rimini, Italy.
Fundación ARDEC, Cartagena de Indias, Colombia.
Oral Maxillofac Surg. 2021 Dec;25(4):477-485. doi: 10.1007/s10006-021-00946-y. Epub 2021 Feb 4.
To evaluate the modifications and possible perforations of the sinus mucosa lining graft particles and implant surfaces after sinus lifting.
Twelve New Zealand rabbits underwent a bilateral sinus lifting using either autogenous bone harvested from the tibia (AB; autogenous bone group) or deproteinized bovine bone mineral (DBBM group) as filler. Implants were simultaneously installed. Thinned sites (<40 μm) and perforations were histologically evaluated at the sinus mucosa in contact with the graft and with the implant after 7 and 40 days of healing.
The mean width of the pristine mucosa was ~70-80 μm. After 7 days of healing, the sinus mucosa in contact with the graft presented fourteen thinned sites in the AB group (mean width 28.8±12.8 μm) and fifty-nine in the DBBM group (mean width 22.2±5.2 μm). No perforations of the mucosa were seen in the AB group while six perforations distributed in two sinuses were found in the DBBM group. After 40 days, only one thinned mucosa and no perforations were observed in the AB group while ninety-six thinned mucosa sites were shared by six sinuses (19.2±3.8 μm), and 3 perforations by two sinuses in the DBBM group. Few sites of the mucosa were in contact with the implant apex and threads after 7 days of healing. However, after 40 days, twelve thinned mucosa sites were seen in four sinuses in the AB groups (mean width ~19 μm) and 5 in two sinuses in the DBBM group (mean width ~20 μm). Perforations were seen in two sinuses in the AB group, and in one sinus in the DBBM group.
The sinus mucosa might be damaged by a close contact with graft particles and implant surface.
评估鼻窦提升术后鼻窦黏膜衬里移植物颗粒和植入物表面的改建和可能穿孔。
12 只新西兰兔双侧行鼻窦提升术，分别使用取自胫骨的自体骨（AB 组，自体骨组）或脱蛋白牛骨矿物质（DBBM 组）作为填充物。同时植入种植体。在愈合后 7 天和 40 天，对与移植物接触和与植入物接触的鼻窦黏膜的变薄部位（<40 μm）和穿孔进行组织学评估。
原始黏膜的平均宽度约为 70-80 μm。愈合后 7 天，与移植物接触的鼻窦黏膜在 AB 组有 14 个变薄部位（平均宽度 28.8±12.8 μm），DBBM 组有 59 个变薄部位（平均宽度 22.2±5.2 μm）。AB 组未见黏膜穿孔，而 DBBM 组有 6 个穿孔分布于 2 个窦腔。愈合 40 天后，AB 组仅观察到 1 个黏膜变薄，无穿孔，6 个窦腔有 96 个黏膜变薄部位（19.2±3.8 μm），2 个窦腔有 3 个穿孔。愈合后 7 天，只有少数黏膜部位与植入物根尖和螺纹接触。然而，40 天后，AB 组的 4 个窦腔中有 12 个黏膜变薄部位（平均宽度约为 19 μm），DBBM 组的 2 个窦腔中有 5 个黏膜变薄部位（平均宽度约为 20 μm）。AB 组的 2 个窦腔和 DBBM 组的 1 个窦腔出现穿孔。
鼻窦黏膜可能因与移植物颗粒和植入物表面紧密接触而受损。
