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肺部超声作为临床疑似 COVID-19 急诊患者的预后工具。

Lung ultrasound as a prognostic tool in emergency patients clinically suspected of COVID-19.

出版信息

Dan Med J. 2021 Jan 7;68(2):A07200551.

Abstract

INTRODUCTION

Tools to quickly triage and evaluate patients with suspected COVID-19 in an emergency department (ED) can improve patient care and reduce risk of overcrowding. The aim of this study was to evaluate if lung ultrasound (LUS) may provide valuable prognostic information in adult patients suspected of COVID-19.

METHODS

A prospective cohort study of adult patients in an ED was conducted. LUS was performed within one hour of the patients' arrival; COVID-19 was defined by a respiratory syndrome coronavirus 2 RNA positive test. The primary outcome was the proportion of patients suspected of COVID-19 and normal LUS with critical outcomes during follow-up, defined as one or more of the following: need of non-invasive ventilation (NIV), invasive mechanical ventilation, intensive care unit (ICU) stay or death. Follow-up was 14 days.

RESULTS

A total of 83 patients were included between 9 March and 12 April 2020. In all, 47 (57%; 95% confidence interval (CI): 45.3-67.5%) had a normal LUS, 46 (98%; 95% CI: 88.7-99.9%) of whom had no critical outcomes. A total of 36 (43%; 95% CI: 32.5-54.7%) had an abnormal LUS, eight of whom (22%; 95% CI: 10.1-39.2%) had critical outcomes. Nine (11%; 95%: CI 5.1-19.6%) had one or more critical outcomes: three on NIV, five in ICUs, four on invasive mechanical ventilation and two died. Among the 12 patients (14%; 95% CI: 7.7-23.9%) tested positive for COVID-19, 11 (92%; 95% CI: 61.5-99.8%) had an abnormal LUS.

CONCLUSIONS

Among adult ED patients suspected of COVID-19, a normal LUS is associated with a low risk of critical outcomes. LUS might be considered for routine use as a prognostic tool in patients suspected of COVID-19.

FUNDING

none.

TRIAL REGISTRATION

not relevant.

摘要

简介

在急诊科(ED)中,能够快速分诊和评估疑似 COVID-19 患者的工具可以改善患者的护理并降低过度拥挤的风险。本研究的目的是评估肺部超声(LUS)是否可为疑似 COVID-19 的成年患者提供有价值的预后信息。

方法

对 ED 中的成年患者进行前瞻性队列研究。患者到达后一小时内进行 LUS 检查;COVID-19 通过呼吸综合征冠状病毒 2 RNA 阳性检测来定义。主要结局是疑似 COVID-19 且 LUS 正常的患者在随访期间出现一个或多个以下情况的比例:需要无创通气(NIV)、有创机械通气、入住重症监护病房(ICU)或死亡。随访时间为 14 天。

结果

2020 年 3 月 9 日至 4 月 12 日期间共纳入 83 例患者。其中,47 例(57%;95%置信区间:45.3-67.5%)LUS 正常,其中 46 例(98%;95%置信区间:88.7-99.9%)无危急情况。36 例(43%;95%置信区间:32.5-54.7%)LUS 异常,其中 8 例(22%;95%置信区间:10.1-39.2%)出现危急情况。9 例(11%;95%置信区间:5.1-19.6%)出现一个或多个危急情况:3 例接受 NIV,5 例入住 ICU,4 例接受有创机械通气,2 例死亡。在 12 例(14%;95%置信区间:7.7-23.9%)COVID-19 检测呈阳性的患者中,11 例(92%;95%置信区间:61.5-99.8%)LUS 异常。

结论

在疑似 COVID-19 的成年 ED 患者中,正常的 LUS 与危急情况的低风险相关。LUS 可考虑作为疑似 COVID-19 患者的常规预后工具。

资金

无。

试验注册

不适用。

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