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2
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本文引用的文献

1
Genetic aspects in schizophrenia. Receptoral theories. Metabolic theories.精神分裂症的遗传学方面。受体理论。代谢理论。
Rom J Morphol Embryol. 2020;61(1):25-32. doi: 10.47162/RJME.61.1.03.
2
THE NEUROENDOCRINOLOGICAL ASPECTS OF PREGNANCY AND POSTPARTUM DEPRESSION.妊娠及产后抑郁的神经内分泌学方面
Acta Endocrinol (Buchar). 2019 Jul-Sep;15(3):410-415. doi: 10.4183/aeb.2019.410.
3
NEUROENDOCRINE INSIGHTS INTO BURNOUT SYNDROME.职业倦怠综合征的神经内分泌学见解
Acta Endocrinol (Buchar). 2019 Jul-Sep;15(3):404-405. doi: 10.4183/aeb.2019.404.
4
Intranasal erythropoietin ameliorates neurological function impairments and neural pathology in mice with chronic alcoholism by regulating autophagy‑related Nrf2 degradation.鼻腔内给予促红细胞生成素可通过调节自噬相关的 Nrf2 降解来改善慢性酒精中毒小鼠的神经功能损伤和神经病理学。
Mol Med Rep. 2019 Feb;19(2):1139-1149. doi: 10.3892/mmr.2018.9706. Epub 2018 Nov 29.
5
DREADD to the Core. Commentary on Purohit et al. (2018): Pharmacogenetic Manipulation of the Nucleus Accumbens Alters Binge-Like Alcohol Drinking in Mice.深入探讨DREADD。对普罗希特等人(2018年)的评论:伏隔核的药物遗传学操纵改变小鼠的暴饮式饮酒行为
Alcohol Clin Exp Res. 2018 Sep;42(9):1623-1626. doi: 10.1111/acer.13822. Epub 2018 Jul 13.
6
Gender dimorphism of brain reward system volumes in alcoholism.酒精中毒患者大脑奖励系统体积的性别二态性。
Psychiatry Res Neuroimaging. 2017 May 30;263:15-25. doi: 10.1016/j.pscychresns.2017.03.001. Epub 2017 Mar 6.
7
The Differential Effects of Alcohol and Nicotine-Specific Nitrosamine Ketone on White Matter Ultrastructure.酒精和尼古丁特异性亚硝胺酮对白质超微结构的不同影响。
Alcohol Alcohol. 2017 Mar 9;52(2):165-171. doi: 10.1093/alcalc/agw067.
8
Source Memory in Korsakoff Syndrome: Disentangling the Mechanisms of Temporal Confusion.柯萨科夫综合征中的源记忆:厘清时间混淆的机制
Alcohol Clin Exp Res. 2017 Mar;41(3):596-607. doi: 10.1111/acer.13318. Epub 2017 Feb 3.
9
Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7.小胶质细胞源性miRNA let-7和高迁移率族蛋白B1通过Toll样受体7(TLR7)促成乙醇诱导的神经毒性。
J Neuroinflammation. 2017 Jan 25;14(1):22. doi: 10.1186/s12974-017-0799-4.
10
Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats.磁共振波谱谷氨酸标志物与海马体酒精戒断后灰质体积之间的负相关:一项人类和大鼠的转化研究
Alcohol Clin Exp Res. 2017 Feb;41(2):323-333. doi: 10.1111/acer.13308. Epub 2017 Jan 18.

酒精中毒的形态病理学方法。

Morphopathological approaches in alcoholism.

机构信息

Department of Psychiatry, Prof. Dr. Alexandru Obregia Clinical Hospital for Psychiatry, Bucharest, Romania;

出版信息

Rom J Morphol Embryol. 2020 Apr-Jun;61(2):345-351. doi: 10.47162/RJME.61.2.04.

DOI:10.47162/RJME.61.2.04
PMID:33544786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7864312/
Abstract

Alcohol morphopathology has been studied over time, being a central interest of specialists, due to the negative consequences it has on the brain and the entire central nervous system (CNS). This paper is a review of the literature that emphasizes one of the problems of the modern world, that of the compulsive consume of alcohol, having a great global spread. The studies analyzed are topical, being carried out in recent years and consider the harmful effects of alcohol on brain formations, such as corpus callosum, gray and white matter, hippocampus, and hypothalamus. At the same time, alcohol is a risk factor for cardiovascular diseases, and in combination with other harmful substances, increases the risk of various diseases, such as neurodegeneration. Abusive alcohol consumption can bring epigenetic changes and alter the typical functioning of cognitive functions. This paper focuses on alcohol consumption on adolescents and young people, which is a serious problem nowadays. Alcohol also influences the way of behavioral expression, becoming a risk for the development of mental disorders. However, alcohol withdrawal is another problem with different effects and must be in the attention of specialists.

摘要

酒精形态病理学一直是专家关注的焦点,因为它对大脑和整个中枢神经系统(CNS)有负面影响。本文是对文献的综述,强调了现代世界的一个问题,即强迫性饮酒的问题,它在全球范围内广泛存在。分析的研究具有针对性,是近年来进行的,并考虑了酒精对大脑结构的有害影响,如胼胝体、灰质和白质、海马体和下丘脑。同时,酒精是心血管疾病的一个危险因素,与其他有害物质结合,会增加各种疾病的风险,如神经退行性疾病。酗酒会带来表观遗传变化,改变认知功能的典型运作方式。本文重点研究了青少年和年轻人的饮酒问题,这是当今的一个严重问题。酒精也会影响行为表现的方式,成为精神障碍发展的一个风险因素。然而,酒精戒断是另一个具有不同影响的问题,必须引起专家的关注。