艾灸对恶性肿瘤化疗后生活质量的影响：系统评价和荟萃分析方案。
Effect of moxibustion on quality of life after chemotherapy in patients with the malignant tumor: A protocol for systematic review and meta analysis.
机构信息
Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province.
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine.
出版信息
Medicine (Baltimore). 2021 Jan 22;100(3):e23471. doi: 10.1097/MD.0000000000023471.
BACKGROUND
The quality of life of patients with malignant tumor can be affected by the severity and treatment of the disease. After chemotherapy, the main symptoms are gastrointestinal reactions, including nausea, vomiting, loss of appetite, and so on, and hematologic response including leukopenia, anemia, and bleeding in severe cases. Currently, moxibustion is conducted to improve the living life of patients after chemotherapy. This article will make a comprehensive and objective discussion in terms of the effect of moxibustion on quality of life after chemotherapy in patients with malignant tumors.
METHODS
After searching the Chinese database (CNKI, VIP, Wanfang Database, and Chinese Biomedical Database) and English database (PubMed, Embase, the Cochrane Library Web of Science), Meta-analysis was performed according to the randomized controlled trial of moxibustion after chemotherapy in patients with malignant tumors. The retrieval time was limited from the time of building the repository to October 2020. Two researchers independently conducted data extraction and quality evaluation of literature on the included studies, and RevMan5.3 was used for Meta-analysis on the included literature.
RESULTS
After analyzing the included literature, this study suggested that by combining chemotherapy with moxibustion, the adverse reactions such as nausea, vomiting, appetite, and insomnia can be relieved. Meanwhile, the psychological burden of patients can be alleviated to a certain extent. Therefore, moxibustion can improve the overall health level and quality of life of patients with malignant tumors.
CONCLUSION
This study will provide evidence-based medical evidence that moxibustion can improve the quality of life after chemotherapy and reduce chemotherapy's adverse reactions in patients with malignant tumors.
ETHICS AND DISSEMINATION
Private information from individuals will not be published. This systematic review also does not involve endangering participant rights. Ethical approval was not required. The results may be published in a peer-reviewed journal or disseminated at relevant conferences.
OSF REGISTRATION NUMBER
DOI 10.17605/OSF.IO/Q5NYM.
背景
恶性肿瘤患者的生活质量会受到疾病严重程度和治疗方式的影响。化疗后，主要症状为胃肠道反应，包括恶心、呕吐、食欲不振等，血液学反应包括白细胞减少、贫血，严重者可出现出血等。目前，艾灸被用于改善化疗后患者的生活质量。本文将从艾灸对恶性肿瘤患者化疗后生活质量的影响方面进行全面、客观的论述。
方法
检索中国数据库（CNKI、VIP、万方数据库、中国生物医学数据库）和英文数据库（PubMed、Embase、the Cochrane Library Web of Science），纳入艾灸联合化疗治疗恶性肿瘤患者的随机对照试验，检索时间限定为建库至 2020 年 10 月。由 2 位研究者独立对纳入研究文献进行数据提取和质量评价，采用 RevMan5.3 对纳入文献进行 Meta 分析。
结果
通过对纳入文献进行分析，提示联合化疗加艾灸可以减轻恶心、呕吐、食欲、失眠等不良反应，同时在一定程度上减轻患者的心理负担，从而提高恶性肿瘤患者的整体健康水平和生活质量。
结论
本研究可为艾灸能够提高恶性肿瘤患者化疗后生活质量、减轻化疗不良反应提供循证医学证据。
伦理与传播
本研究不会公布个人信息。本系统评价也不会危及参与者的权利。不需要伦理批准。研究结果可能会发表在同行评议的期刊上，或在相关会议上传播。OSF 注册号：DOI 10.17605/OSF.IO/Q5NYM。
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