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酶联免疫吸附试验 3 检测血清乙型肝炎病毒标志物在乙型肝炎诊断中的价值:系统评价和荟萃分析方案。

Value of anti-hepatitis B virus in serum tested by enzyme linked immunosorbent assay 3 in diagnosis of hepatitis B: A protocol for systemic review and meta analysis.

机构信息

Department of Medical Laboratory Technology, Luoyang Polytechnic.

Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Army Medical University.

出版信息

Medicine (Baltimore). 2021 Jan 22;100(3):e23961. doi: 10.1097/MD.0000000000023961.

DOI:10.1097/MD.0000000000023961
PMID:33545977
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7837889/
Abstract

INTRODUCTION

This protocol is for a meta analysis that aims to systematically review the diagnostic value of anti-hepatitis B virus in serum tested by the enzyme linked immunosorbent assay in patients with hepatitis B.

METHODS AND ANALYSIS

The following electronic databases will be searched from inception to Mar 2021: PubMed, Web of Science, ScienceDirect, EMBASE, MEDLINE, Springer, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Chinese Science and Technology Periodical Database, and Wanfang Database. All study about enzyme linked immunosorbent assay reagents have been published at home and abroad to diagnose hepatitis B virus will be included. MetaDisc 1.4 soft will used to calculate pooled effect size in sensitivity, specifi city, likelihood ratio, diagnostic odds ratio and summary receiver operating characteristic curve, and area under the curve as well.

ETHICS AND DISSEMINATION

Formal ethical approval is not required, as the data are not individualized. The findings of this systematic review will be disseminated in a peer-reviewed publication and/or presented at relevant conferences.

REGISTRATION NUMBER

INPLASY2020100051.

摘要

简介

本方案是一项荟萃分析,旨在系统地回顾通过酶联免疫吸附试验检测血清中乙型肝炎病毒的抗乙型肝炎病毒的诊断价值。

方法和分析

将从建库到 2021 年 3 月在以下电子数据库中进行检索:PubMed、Web of Science、ScienceDirect、EMBASE、MEDLINE、Springer、中国知网、中国生物医学文献数据库、维普中文科技期刊数据库和万方数据库。所有国内外发表的关于酶联免疫吸附试验试剂诊断乙型肝炎病毒的研究都将被纳入。使用 MetaDisc 1.4 软件计算汇总敏感性、特异性、似然比、诊断比值比和综合受试者工作特征曲线以及曲线下面积。

伦理和传播

由于数据没有个体化,因此不需要正式的伦理批准。本系统评价的结果将发表在同行评议的出版物中,并/或在相关会议上展示。

注册号

INPLASY2020100051。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dca/7837889/4933c8f0a512/medi-100-e23961-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dca/7837889/4933c8f0a512/medi-100-e23961-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dca/7837889/4933c8f0a512/medi-100-e23961-g001.jpg

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