Alshammari Hatem, Neilands Jessica, Svensäter Gunnel, Stavropoulos Andreas
Department of Periodontology, Faculty of Odontology, Malmö University, SE-205 06 Malmö, Sweden.
Section for Oral Biology and Pathology, Faculty of Odontology, Malmö University, SE-205 06 Malmö, Sweden.
Antibiotics (Basel). 2021 Feb 3;10(2):150. doi: 10.3390/antibiotics10020150.
: Peri-implantitis due to infection of dental implants is a common complication that may cause significant patient morbidity. In this study, we investigated the antimicrobial potential of Sr(OH) against different bacteria associated with peri-implantitis. : The antimicrobial potential of five concentrations of Sr(OH) (100, 10, 1, 0.1, and 0.01 mM) was assessed with agar diffusion test, minimal inhibitory concentration (MIC), and biofilm viability assays against six bacteria commonly associated with biomaterial infections: , , , , , and . : Zones of inhibition were only observed for, 0.01, 0.1, and 1 mM of Sr(OH) tested against , in the agar diffusion test. Growth inhibition in planktonic cultures was achieved at 10 mM for all species tested ( < 0.001). In biofilm viability assay, 10 and 100 mM Sr(OH) showed potent bactericidal affect against , , , , and . : The findings of this study indicate that Sr(OH) has antimicrobial properties against bacteria associated with peri-implantitis.
由于牙种植体感染导致的种植体周围炎是一种常见并发症，可能会给患者带来严重的健康问题。在本研究中，我们调查了氢氧化锶（Sr(OH)）对与种植体周围炎相关的不同细菌的抗菌潜力。：采用琼脂扩散试验、最低抑菌浓度（MIC）和生物膜活力测定法，评估了五种浓度（100、10、1、0.1和0.01 mM）的Sr(OH)对六种通常与生物材料感染相关的细菌的抗菌潜力：，，，，，和。：在琼脂扩散试验中，仅观察到针对测试的0.01、0.1和1 mM Sr(OH)对有抑菌圈。对于所有测试菌种，在10 mM时浮游培养物中的生长受到抑制（<0.001）。在生物膜活力测定中，10和100 mM Sr(OH)对，，，，和显示出强大的杀菌作用。：本研究结果表明，Sr(OH)对与种植体周围炎相关的细菌具有抗菌特性。
