Beaudoin Meggie Lallier, Renaud Christian, Boucher Marc, Kakkar Fatima, Gantt Soren, Boucoiran Isabelle
Department of Obstetrics and Gynecology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
Department of Microbiology, Infectiology & Immunology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada; Women and Children Infectious Diseases Centre, CHU Sainte-Justine, Montreal, Quebec, Canada.
Eur J Obstet Gynecol Reprod Biol. 2021 Mar;258:409-413. doi: 10.1016/j.ejogrb.2021.01.035. Epub 2021 Jan 27.
To assess the choice and attitude of pregnant women regarding CMV serological screening and CMV prevention behaviors in pregnancy.
In this cross-sectional study, pregnant women were recruited in a single center during routine prenatal screening tests at 11-16 weeks. Participants filled out a questionnaire assessing knowledge about congenital CMV (cCMV) infection, risk perception and willingness to have CMV serological screening as well as their attitude toward CMV prevention behaviors.
Among 234 pregnant women, 74.4 % (95 % confidence interval: 68.8-80.0 %) wanted CMV serological screening in pregnancy. The factors significantly associated with the desire for screening were perceived risk and perceived severity of cCMV. An informed choice regarding CMV screening (value-consistent, based on good knowledge and deliberated) was performed by 54 % of women who chose the screening and 30 % of women who declined the screening (p = 0.039). The median scores regarding attitudes toward CMV prevention behaviors were 3.7/5 for avoiding sharing behaviors and 4.0/5 for not kissing a child on the lips.
The majority of pregnant women want to have CMV serological screening once informed about congenital CMV infection. New tools need to be developed to allow for informed choice regarding CMV serological screening in pregnancy.
评估孕妇对巨细胞病毒（CMV）血清学筛查的选择和态度以及孕期CMV预防行为。
在这项横断面研究中，于孕11 - 16周进行常规产前筛查时在单一中心招募孕妇。参与者填写一份问卷，评估其对先天性CMV（cCMV）感染的知识、风险认知以及进行CMV血清学筛查的意愿，还有她们对CMV预防行为的态度。
在234名孕妇中，74.4%（95%置信区间：68.8 - 80.0%）希望在孕期进行CMV血清学筛查。与筛查意愿显著相关的因素是对cCMV的感知风险和感知严重性。54%选择筛查的女性和30%拒绝筛查的女性做出了关于CMV筛查的明智选择（基于充分知识和审慎考虑且符合价值观）（p = 0.039）。对于CMV预防行为态度的中位数得分，避免共享行为为3.7/5，不亲吻孩子嘴唇为4.0/5。
一旦了解先天性CMV感染，大多数孕妇希望进行CMV血清学筛查。需要开发新工具以实现孕期CMV血清学筛查的明智选择。
