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1
Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing.2019 年冠状病毒病(COVID-19)通过全基因组测序确认为与严重急性呼吸综合征冠状病毒 2 株系不同的病毒再次感染。
Clin Infect Dis. 2021 Nov 2;73(9):e2946-e2951. doi: 10.1093/cid/ciaa1275.
2
Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study.西班牙 2020 年人群血清流行病学研究(ENE-COVID):全国范围内基于人群的血清流行病学研究。
Lancet. 2020 Aug 22;396(10250):535-544. doi: 10.1016/S0140-6736(20)31483-5. Epub 2020 Jul 6.
3
Ethical Implementation of Immunity Passports During the COVID-19 Pandemic.《COVID-19 大流行期间免疫护照的伦理实施》
J Infect Dis. 2020 Aug 4;222(5):715-718. doi: 10.1093/infdis/jiaa352.
4
Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study.瑞士日内瓦抗 SARS-CoV-2 IgG 抗体的血清流行率(SEROCoV-POP):一项基于人群的研究。
Lancet. 2020 Aug 1;396(10247):313-319. doi: 10.1016/S0140-6736(20)31304-0. Epub 2020 Jun 11.
5
Waiting for Certainty on Covid-19 Antibody Tests - At What Cost?等待新冠病毒抗体检测结果确定——代价几何?
N Engl J Med. 2020 Aug 6;383(6):e37. doi: 10.1056/NEJMp2017739. Epub 2020 Jun 5.
6
Ten reasons why immunity passports are a bad idea.免疫护照不可行的十个原因。
Nature. 2020 May;581(7809):379-381. doi: 10.1038/d41586-020-01451-0.
7
Preparing for a responsible lockdown exit strategy.为负责任的封控退出策略做好准备。
Nat Med. 2020 May;26(5):643-644. doi: 10.1038/s41591-020-0871-y.
8
Chile plans controversial COVID-19 certificates.智利计划推出备受争议的新冠病毒证书。
Lancet. 2020 May 9;395(10235):1473. doi: 10.1016/S0140-6736(20)31096-5.
9
COVID-19 immunity passports and vaccination certificates: scientific, equitable, and legal challenges.新冠病毒免疫护照与疫苗接种证书:科学、公平及法律挑战
Lancet. 2020 May 23;395(10237):1595-1598. doi: 10.1016/S0140-6736(20)31034-5. Epub 2020 May 4.
10
Privileges and Immunity Certification During the COVID-19 Pandemic.新冠疫情期间的特权与豁免证明
JAMA. 2020 Jun 9;323(22):2243-2244. doi: 10.1001/jama.2020.7712.

新冠病毒感染免疫认证:伦理考量。

Immunity certification for COVID-19: ethical considerations.

机构信息

Centre for Biomedical Ethics, National University of Singapore, Blk MD 11, 10 Medical Drive #02-03, Singapore117597, Singapore.

Health Ethics and Governance Unit, World Health Organization, Geneva, Switzerland.

出版信息

Bull World Health Organ. 2021 Feb 1;99(2):155-161. doi: 10.2471/BLT.20.280701. Epub 2020 Dec 1.

DOI:10.2471/BLT.20.280701
PMID:33551509
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7856365/
Abstract

Restrictive measures imposed because of the coronavirus disease 2019 (COVID-19) pandemic have resulted in severe social, economic and health effects. Some countries have considered the use of immunity certification as a strategy to relax these measures for people who have recovered from the infection by issuing these individuals a document, commonly called an immunity passport. This document certifies them as having protective immunity against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus that causes COVID-19. The World Health Organization has advised against the implementation of immunity certification at present because of uncertainty about whether long-term immunity truly exists for those who have recovered from COVID-19 and concerns over the reliability of the proposed serological test method for determining immunity. Immunity certification can only be considered if scientific thresholds for assuring immunity are met, whether based on antibodies or other criteria. However, even if immunity certification became well supported by science, it has many ethical issues in terms of different restrictions on individual liberties and its implementation process. We examine the main considerations for the ethical acceptability of immunity certification to exempt individuals from restrictive measures during the COVID-19 pandemic. As well as needing to meet robust scientific criteria, the ethical acceptability of immunity certification depends on its uses and policy objectives and the measures in place to reduce potential harms, and prevent disproportionate burdens on non-certified individuals and violation of individual liberties and rights.

摘要

由于 2019 年冠状病毒病(COVID-19)大流行而实施的限制措施对社会、经济和健康造成了严重影响。一些国家考虑使用免疫证明作为一种策略,为从感染中康复的人放松这些措施,为这些人颁发一份文件,通常称为免疫护照。该文件证明他们对导致 COVID-19 的严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)具有保护免疫力。世界卫生组织目前建议不要实施免疫认证,因为不确定 COVID-19 康复者是否真的具有长期免疫力,以及对拟议的用于确定免疫力的血清学测试方法的可靠性的担忧。只有在基于抗体或其他标准确保免疫的科学阈值得到满足的情况下,才能考虑免疫认证。然而,即使免疫认证得到科学的充分支持,它在个人自由方面的不同限制及其实施过程中也存在许多伦理问题。我们研究了在 COVID-19 大流行期间豁免个人限制措施的免疫认证的伦理可接受性的主要考虑因素。除了需要满足严格的科学标准外,免疫认证的伦理可接受性还取决于其用途和政策目标以及为减少潜在危害而采取的措施,以防止非认证个人承担不成比例的负担和侵犯个人自由和权利。