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[基于针对贝宁普通人群的筛查活动数据确定的乙型病毒性肝炎血清流行率及其相关因素]

[Seroprevalence of viral hepatitis B and its associated factors determined based on data from a screening campaign targeting the general population in Benin].

作者信息

Kpossou Aboudou Raïmi, Paraiso Moussiliou Noel, Sokpon Comlan N'déhougbèa, Alassan Khadidjatou Saké, Vignon Rodolph Koffi, Keke René Kpemahouton, Bigot Cédric, Domonhédo Camille, Sossa Gbédo Edmond, Séhonou Jean, Kodjoh Nicolas, Lawin Hervé

机构信息

Faculté des Sciences de la Santé, Université d´Abomey-Calavi, Cotonou, Bénin.

Centre National Hospitalier et Universitaire Hubert Koutoukou Maga de Cotonou, Cotonou, Bénin.

出版信息

Pan Afr Med J. 2020 Nov 18;37:247. doi: 10.11604/pamj.2020.37.247.26070. eCollection 2020.

DOI:10.11604/pamj.2020.37.247.26070
PMID:33552365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7847212/
Abstract

INTRODUCTION

hepatitis B is a global public health problem. The purpose of this study was to determine the prevalence of hepatitis B virus (HBV) and its associated factors based on data from a mass screening in several localities across Benin.

METHOD

we conducted a cross-sectional descriptive and analytical study with prospective data collection. Data collection was carried out during voluntary free hepatitis B screening organized by the Rotary Club in 23 localities across Benin from the 20 to 28 July 2019. Rapid test for diagnostic orientation was used for the detection of HBs antigen.

RESULTS

a total of 9035 volunteers were included in the study. They were mostly of Benin origin (99%), with a mean age of 27 years; 51.1% of them were singles, mainly schoolchildren, pupils or students (37.9%). HBV seroprevalence was 6% (545/9035) [95%CI=5.5%-6.5%]. In univariate analysis, factors associated with HBs Ag colonization were: age, sex, marital status, education level, occupation and a history of diabetes, scarification and hepatitis C, while in multivariate analysis they were: sex, age and education level.

CONCLUSION

HBV seroprevalence is 6% in the study population. HBV infection mainly affects male subjects over 17 years of age with secondary-level education.

摘要

引言

乙型肝炎是一个全球性的公共卫生问题。本研究的目的是根据贝宁多个地区大规模筛查的数据,确定乙型肝炎病毒(HBV)的流行率及其相关因素。

方法

我们进行了一项横断面描述性和分析性研究,并进行前瞻性数据收集。数据收集于2019年7月20日至28日在贝宁23个地区由扶轮社组织的自愿免费乙型肝炎筛查期间进行。采用诊断定向快速检测法检测HBs抗原。

结果

共有9035名志愿者纳入研究。他们大多来自贝宁(99%),平均年龄27岁;其中51.1%为单身,主要是学童、小学生或学生(37.9%)。HBV血清流行率为6%(545/9035)[95%CI=5.5%-6.5%]。单因素分析中,与HBs Ag定植相关的因素有:年龄、性别、婚姻状况、教育水平、职业以及糖尿病史、划痕接种史和丙型肝炎史,而多因素分析中相关因素为:性别、年龄和教育水平。

结论

研究人群中HBV血清流行率为6%。HBV感染主要影响17岁以上具有中学教育水平的男性受试者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c855/7847212/cc5ca281560d/PAMJ-37-247-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c855/7847212/cc5ca281560d/PAMJ-37-247-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c855/7847212/cc5ca281560d/PAMJ-37-247-g001.jpg

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