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一名具有原发性干燥综合征临床和组织学特征的患者出现结节病。

Sarcoidosis in a patient presenting with clinical and histological features of primary Sjögren's syndrome.

作者信息

Melsom R D, Speight P M, Ryan J, Perry J D

机构信息

Department of Rheumatology, London Hospital.

出版信息

Ann Rheum Dis. 1988 Feb;47(2):166-8. doi: 10.1136/ard.47.2.166.

DOI:10.1136/ard.47.2.166
PMID:3355252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1003471/
Abstract

A patient presenting with bilateral enlargement of parotid and lacrimal glands, xerostomia, and keratoconjunctiva sicca, whose labial biopsy specimen showed changes consistent with Sjögren's syndrome, is described. The patient was initially misdiagnosed as having primary Sjögren's syndrome (SS). Subsequent investigations, however, performed to exclude an associated lymphoma or sarcoidosis, showed histological changes of the latter. The possibility that early infiltrates of the salivary glands in sarcoid may mimic those of SS is discussed.

摘要

描述了一名患者,其表现为双侧腮腺和泪腺肿大、口干症以及角结膜干燥症,唇活检标本显示的变化与干燥综合征相符。该患者最初被误诊为原发性干燥综合征(SS)。然而,随后为排除相关淋巴瘤或结节病而进行的检查显示为后者的组织学变化。文中讨论了结节病早期唾液腺浸润可能酷似干燥综合征浸润的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ab7/1003471/13da1aad18e4/annrheumd00412-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ab7/1003471/bc9c84810da6/annrheumd00412-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ab7/1003471/13da1aad18e4/annrheumd00412-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ab7/1003471/bc9c84810da6/annrheumd00412-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ab7/1003471/13da1aad18e4/annrheumd00412-0080-a.jpg

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Sarcoidosis in a patient presenting with clinical and histological features of primary Sjögren's syndrome.一名具有原发性干燥综合征临床和组织学特征的患者出现结节病。
Ann Rheum Dis. 1988 Feb;47(2):166-8. doi: 10.1136/ard.47.2.166.
2
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引用本文的文献

1
Sarcoidosis or primary Sjögren's syndrome?结节病还是原发性干燥综合征?
Ann Rheum Dis. 1988 Nov;47(11):965-6. doi: 10.1136/ard.47.11.965.
2
Primary Sjögren's syndrome presenting as a case of sarcoidosis and a suspected pancreatic tumour.以结节病和疑似胰腺肿瘤病例形式出现的原发性干燥综合征。
Ann Rheum Dis. 1990 Jun;49(6):407-9. doi: 10.1136/ard.49.6.407.

本文引用的文献

1
ENLARGEMENT OF PAROTID GLAND DUE TO SARCOIDOSIS.结节病所致腮腺肿大
Br Med J. 1964 Oct 3;2(5413):861-2. doi: 10.1136/bmj.2.5413.861.
2
TASS syndrome: unusual association of thyroiditis, Addison's disease, Sjögren's syndrome and sarcoidosis.TASS综合征:甲状腺炎、艾迪生病、干燥综合征和结节病的罕见关联。
J R Soc Med. 1983 Oct;76(10):883-5.
3
Multinucleate giant cells in sublabial salivary gland tissue in Sjögren's syndrome. A diagnostic pitfall.干燥综合征下唇唾液腺组织中的多核巨细胞。一个诊断陷阱。
Virchows Arch A Pathol Anat Histopathol. 1984;403(3):247-56. doi: 10.1007/BF00694901.
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Labial salivary gland biopsy in Sjögren's disease.干燥综合征的唇唾液腺活检
J Clin Pathol. 1968 Sep;21(5):656-60. doi: 10.1136/jcp.21.5.656.
5
Lymphocytic sialadenitis in the major and minor glands: a correlation in postmortem subjects.大、小唾液腺的淋巴细胞性涎腺炎:尸检对象中的相关性
J Clin Pathol. 1970 Nov;23(8):690-4. doi: 10.1136/jcp.23.8.690.
6
Minor salivary gland involvement in Sjögren's syndrome.干燥综合征中的小唾液腺受累情况。
Oral Surg Oral Med Oral Pathol. 1974 Jan;37(1):64-74. doi: 10.1016/0030-4220(74)90160-1.
7
Minor salivary gland involvement in sarcoidosis. Report of 3 cases with positive lip biopsies.
Oral Surg Oral Med Oral Pathol. 1972 May;33(5):755-62. doi: 10.1016/0030-4220(72)90443-4.
8
Labial minor salivary gland biopsy: a highly discriminatory diagnostic method between sarcoidosis and Sjögren's syndrome.唇小唾液腺活检:结节病与干燥综合征之间的一种高度鉴别性诊断方法。
Respiration. 1986;50(2):102-7. doi: 10.1159/000194916.
9
Urinary monoclonal free light chains in primary Sjögren's syndrome: an aid to the diagnosis of malignant lymphoma.原发性干燥综合征中的尿单克隆游离轻链:对恶性淋巴瘤诊断的辅助作用
Ann Rheum Dis. 1986 Mar;45(3):210-9. doi: 10.1136/ard.45.3.210.
10
Gougerot-Sjögren syndrome and sarcoidosis.
Ann N Y Acad Sci. 1976;278:401-5. doi: 10.1111/j.1749-6632.1976.tb47051.x.