Fujimoto Yo, Katayama Yasumi, Gyotoku Yoshinori, Oura Ryosuke, Kobori Ikuhiro, Kitagawa Tomoyuki, Tamano Masaya
Department of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City Japan.
Endoscopy Center Dokkyo Medical University Saitama Medical Center Koshigaya City Japan.
JGH Open. 2020 Dec 23;5(2):280-285. doi: 10.1002/jgh3.12485. eCollection 2021 Feb.
Based on past diagnostic classifications of gastritis, the Kyoto classification of gastritis adopts simpler, more objective gastritis findings according to infection status and evaluates the risk of gastric cancer. To clarify whether this score can predict future gastric cancer, we retrospectively examined risk scores obtained using the Kyoto classification of gastritis a few years prior to the diagnosis of early gastric cancer.
We reviewed data from 50 individuals who had undergone upper gastrointestinal endoscopy 2-3 years prior to the diagnosis of early gastric cancer in our hospital. Two expert endoscopists evaluated and compared risk scores obtained using the Kyoto classification of gastritis between cancer and control groups.
With regard to the risk score obtained using the Kyoto classification of gastritis in all cases, atrophy, intestinal metaplasia, diffuse redness, and total score were significantly higher among gastric cancer cases. Among -eradicated cases, atrophy score was higher in the gastric cancer group. Among patients for whom had been eradicated for >3 years at first endoscopy, atrophy score was still higher in the gastric cancer group.
This retrospective study suggested that the risk score obtained using the Kyoto classification of gastritis was useful for predicting the onset of gastric cancer. In particular, patients with a high atrophy score even after eradication may be at high risk of developing gastric cancer.
基于既往胃炎诊断分类，胃炎京都分类根据感染状况采用更简单、更客观的胃炎表现，并评估胃癌风险。为明确该评分是否能预测未来胃癌，我们回顾性研究了在早期胃癌诊断前数年使用胃炎京都分类获得的风险评分。
我们回顾了我院50例在早期胃癌诊断前2 - 3年接受上消化道内镜检查的患者的数据。两位专家内镜医师评估并比较了癌症组和对照组使用胃炎京都分类获得的风险评分。
在所有病例中，就使用胃炎京都分类获得的风险评分而言，胃癌病例的萎缩、肠化生、弥漫性发红及总分显著更高。在根除治疗的病例中，胃癌组的萎缩评分更高。在内镜检查时首次根除治疗已超过3年的患者中，胃癌组的萎缩评分仍然更高。
这项回顾性研究表明，使用胃炎京都分类获得的风险评分有助于预测胃癌的发生。特别是，即使在根除治疗后萎缩评分仍高的患者可能发生胃癌的风险较高。
