eradication improved the Kyoto classification score on endoscopy.

BACKGROUND AND AIM

Endoscopy-based Kyoto classification predicts the risk of infection and gastric cancer; however, the change in score following eradication remains unknown. We retrospectively compared the Kyoto score before and after eradication.

METHODS

positive patients who underwent baseline esophagogastroduodenoscopy (EGD), successful eradication, and surveillance EGD were enrolled. The Kyoto score is a sum of scores for atrophy (Kimura-Takemoto atrophic-border classification none or C1: 0, C-II or C-III: 1, O-I to O-III: 2), intestinal metaplasia (none: 0, antrum: 1, corpus and antrum: 2), enlarged folds (absence: 0, presence: 1), nodularity (absence: 0, presence: 1), and diffuse redness (none: 0, mild: 1, severe: 2) and ranges from 0 to 8.

RESULTS

Eighty-three patients (mean age: 54.9 years; 65.1% women) were enrolled. The mean duration from successful eradication to surveillance EGD was 256 days. The Kyoto score significantly decreased from 3.90 to 2.78 following eradication ( < 0.001). Scores for endoscopic atrophy (from 1.43 to 1.46, = 0.638) and endoscopic intestinal metaplasia (from 0.53 to 0.47, = 0.543) did not change; however, there was significant improvement in the scores for enlarged folds (from 0.14 to 0.00, = 0.002), nodularity (from 0.18 to 0.04, = 0.002), and diffuse redness (from 1.61 to 0.82,  < 0.001).

CONCLUSION

The Kyoto classification score decreased following eradication. A decrease in the scores for enlarged folds, nodularity, and diffuse redness contributed to the decrease in Kyoto score.