日间小睡与糖尿病风险的关联：来自中国浙江一项前瞻性研究的证据。
Association of daytime napping in relation to risk of diabetes: evidence from a prospective study in Zhejiang, China.
作者信息
Wang Hao, Chen Lingli, Shen Dun, Cao Yuan, Zhang Xiaoyi, Xie Kaixu, Wang Chunmei, Zhu Shuiqing, Guo Yu, Fiona Bragg, Yu Min, Chen Zhengming, Li Liming
机构信息
Department of NCDs Control and Prevention, Zhejiang Provincial Center for Diseases Control and Prevention, #3399 Binsheng Road, Binjiang District, Hangzhou, Zhejiang Province, China.
Department of NCDS Control and Prevention, Tongxiang City Center for Disease Control and Prevention, Tongxiang, China.
出版信息
Nutr Metab (Lond). 2021 Feb 8;18(1):18. doi: 10.1186/s12986-021-00545-4.
BACKGROUND
Diabetes was a major risk factor for numerous chronic diseases. However, the associations between daytime napping and diabetes in the existing literature is still inconsistent.
METHODS
The analysis included 53,916 participants aged 30-79 years of the China Kadoorie Biobank prospective study from Tongxiang. Incident diabetes were identified through linkage with incident diabetes surveillance systems, health insurance system, and death registries. Cox regressions were used to estimate the associations of daytime napping with diabetes.
RESULTS
5.11% of participants reported habitual daytime napping. During 488,233 person-years (median 9.4 years) of follow-up, 3333 incident diabetes, including 1249 males and 2084 females, were documented. After adjusting for socio-demographic status, behavioral lifestyle, BMI, waist circumference and snoring, as comparison with those without daytime napping, the hazard ratios for risk of diabetes were 1.39 (95% CI 1.21-1.59). The corresponding figures for males and females were 1.45 (95% CI 1.20-1.74) and 1.30 (95% CI 1.05-1.59), respectively. The corresponding figures for postmenopausal and premenopausal females were 1.41 (95% CI 1.08-1.80) and 1.13 (95% CI 0.78-1.59), respectively.
CONCLUSIONS
Habitual daytime napping is positively associated with risk of diabetes in adults, except premenopausal females.
背景
糖尿病是多种慢性疾病的主要风险因素。然而，现有文献中关于白天小睡与糖尿病之间的关联仍不一致。
方法
分析纳入了来自桐乡的中国嘉道理生物银行前瞻性研究中53916名年龄在30 - 79岁的参与者。通过与糖尿病发病监测系统、健康保险系统和死亡登记处的联动来确定新发糖尿病病例。采用Cox回归分析来估计白天小睡与糖尿病之间的关联。
结果
5.11%的参与者报告有习惯性白天小睡。在488233人年（中位随访时间9.4年）的随访期间，记录了3333例新发糖尿病病例，其中男性1249例，女性2084例。在调整了社会人口统计学状况、行为生活方式、体重指数、腰围和打鼾情况后，与无白天小睡的人相比，糖尿病风险的风险比为1.39（95%置信区间1.21 - 1.59）。男性和女性的相应数值分别为1.45（95%置信区间1.20 - 1.74）和1.30（95%置信区间1.05 - 1.59）。绝经后和绝经前女性的相应数值分别为1.41（95%置信区间1.08 - 1.80）和1.13（95%置信区间0.78 - 1.59）。
结论
习惯性白天小睡与成年人患糖尿病的风险呈正相关，但绝经前女性除外。
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