Zhang Renhua, Zhou Enhui, Liu Leilei, Wang Yuan, Xiao Fei, Hong Feng
School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, China.
Front Endocrinol (Lausanne). 2025 Apr 28;16:1563944. doi: 10.3389/fendo.2025.1563944. eCollection 2025.
Limited information is available on the effect of nap duration and hypertension-diabetes comorbidity (HDC) in minority people. We aimed to explore the relationship between nap duration and HDC for the co-management of hypertension and diabetes mellitus in the minority.
A total of 16,911 participants from the China Multi-Ethnic Cohort (CMEC) were enrolled in this cross-sectional study. Nap duration was then categorized into four groups: 0 hours (reference group), 0-0.5 hours, 0.5-1 hour, and >1 hour. Multiple logistic regression was applied to analyze the association between nap duration and HDC. Restricted cubic splines (RCS) analysis was conducted to assess the nonlinear relationship between nap duration and the co-occurrence of HDC. Subgroup analyses were subsequently performed, stratified by sex, age, and ethnicity.
Among 16,911 participants with a median age of 51.79 years, of whom 66.00% were female. A total of 647 subjects were in the HDC group, representing a prevalence rate of 3.83% in the entire study population. Multivariate logistic regression analysis showed that, after multivariate adjustments, the odds ratios (95% CI) for HDC across the four groups (0h, 0-0.5h, 0.5-1h and > 1h) were: reference, 1.305 (1.027, 1.650), 1.254 (1.016, 1.542), 1.612 (1.261, 2.046), respectively. RCS analyses revealed distinct associations between naptime duration and HDC: no significant relationship in participants aged <45 years (overall=0.529); a linear positive correlation in those aged 45-60 years (overall=0.001); and an inverse J-shaped association peaking at 60 minutes in individuals aged >60 years (overall=0.026, nonlinearity=0.015). The subgroup analysis revealed that among >45 years, male, Dong or Miao, a longer nap duration was also associated with an increased prevalence risk of HDC.
Longer napping duration were associated with an increased risk of HDC and monitoring nap duration may aid in identifying high-risk groups.
关于午睡时长与少数民族人群高血压-糖尿病合并症（HDC）之间关系的信息有限。我们旨在探讨午睡时长与HDC之间的关系，以便对少数民族的高血压和糖尿病进行联合管理。
本横断面研究纳入了来自中国多民族队列（CMEC）的16911名参与者。午睡时长随后被分为四组：0小时（参照组）、0 - 0.5小时、0.5 - 1小时和>1小时。应用多因素逻辑回归分析午睡时长与HDC之间的关联。进行限制立方样条（RCS）分析以评估午睡时长与HDC并发之间的非线性关系。随后按性别、年龄和种族进行亚组分析。
在16911名年龄中位数为51.79岁的参与者中，66.00%为女性。共有647名受试者处于HDC组，在整个研究人群中的患病率为3.83%。多因素逻辑回归分析表明，经过多因素调整后，四组（0小时、0 - 0.5小时、0.5 - 1小时和>1小时）HDC的比值比（95%CI）分别为：参照，1.305（1.027，1.650），1.254（1.016，1.542），1.612（1.261，2.046）。RCS分析揭示了午睡时长与HDC之间的不同关联：<45岁参与者中无显著关系（总体=0.529）；45 - 60岁参与者中呈线性正相关（总体=0.001）；>60岁个体中呈倒J形关联，在60分钟时达到峰值（总体=0.026，非线性=0.015）。亚组分析显示，在>45岁、男性、侗族或苗族人群中，较长的午睡时长也与HDC患病率风险增加相关。
较长的午睡时长与HDC风险增加相关，监测午睡时长可能有助于识别高危人群。
