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Considering Personalized Interferon Beta Therapy for COVID-19.

作者信息

Dorgham Karim, Neumann Avidan U, Decavele Maxens, Luyt Charles-Edouard, Yssel Hans, Gorochov Guy

机构信息

Sorbonne Université, Inserm, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France

Department of Environmental Medicine, Faculty of Medicine, Universitätsklinikum Augsburg, Augsburg, Germany.

出版信息

Antimicrob Agents Chemother. 2021 Mar 18;65(4). doi: 10.1128/AAC.00065-21.

DOI:10.1128/AAC.00065-21
PMID:33558300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8097459/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa73/8097459/12d348977cdc/AAC.00065-21-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa73/8097459/12d348977cdc/AAC.00065-21-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa73/8097459/12d348977cdc/AAC.00065-21-f0001.jpg

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N Engl J Med. 2020 Dec 10;383(24):2389-2390. doi: 10.1056/NEJMc2031085. Epub 2020 Nov 20.
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Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial.吸入用干扰素 β-1a（SNG001）治疗 SARS-CoV-2 感染的安全性和有效性：一项随机、双盲、安慰剂对照、2 期临床试验。
Lancet Respir Med. 2021 Feb;9(2):196-206. doi: 10.1016/S2213-2600(20)30511-7. Epub 2020 Nov 12.
3
Interferon Beta-1b and Lopinavir-Ritonavir for Middle East Respiratory Syndrome.
鼻咽型 I 型干扰素用于即时预防新发呼吸道病毒感染。
Front Immunol. 2021 May 19;12:660298. doi: 10.3389/fimmu.2021.660298. eCollection 2021.
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Reply to Dorgham et al., "Considering Personalized Interferon Beta Therapy for COVID-19".对多尔加姆等人《考虑针对新冠肺炎的个性化干扰素β治疗》一文的回复
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β-1b 干扰素联合洛匹那韦利托那韦治疗中东呼吸综合征
N Engl J Med. 2020 Oct 22;383(17):1645-1656. doi: 10.1056/NEJMoa2015294. Epub 2020 Oct 7.
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Autoantibodies against type I IFNs in patients with life-threatening COVID-19.COVID-19 危重症患者体内针对 I 型干扰素的自身抗体。
Science. 2020 Oct 23;370(6515). doi: 10.1126/science.abd4585. Epub 2020 Sep 24.
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