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罕见 von Willebrand 病致血泣症 1 例并文献复习

A Rare Case of von Willebrand Disease Presenting as Hemolacria and Literature Review.

机构信息

Department of Ophthalmology, Faculty of Medicine.

Department of Paediatrics, Faculty of Medicine.

出版信息

J Pediatr Hematol Oncol. 2021 Apr 1;43(3):101-103. doi: 10.1097/MPH.0000000000002077.

DOI:10.1097/MPH.0000000000002077
PMID:33560075
Abstract

Hemolacria is a rare condition that causes a person to produce tears that are partially composed of blood. It can be a presenting feature of certain ocular and systemic conditions. Here, the authors describe an interesting case of a 12-year-old boy with an underlying beta-thalassemia trait, who presented with a 2-day history of bilateral blood-stained tears, and an episode of epistaxis. Ocular examination was normal, and syringing showed no nasolacrimal duct blockage. Systemic examination was unremarkable. Laboratory investigations confirmed type 2 von Willebrand disease. Management of hemolacria remains a clinical challenge given the rare occurrence of the disease. In this case report, the authors discuss the differential diagnosis and management approach to hemolacria.

摘要

血泪症是一种罕见的病症,会导致患者的眼泪中部分含有血液。它可能是某些眼部和全身性疾病的主要特征。在此,作者描述了一例有趣的病例,一名 12 岁男孩患有潜在的β-地中海贫血特征,他出现了两天的双侧血泪,并伴有鼻出血。眼部检查正常,冲洗没有发现鼻泪管堵塞。全身检查无异常。实验室检查证实为 2 型血管性血友病。鉴于该病的罕见发生,血泪症的治疗仍然是一个临床挑战。在本病例报告中,作者讨论了血泪症的鉴别诊断和治疗方法。

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