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[大鼠睡眠-觉醒周期中巨细胞被盖区单位活动的动态变化]

[Dynamics of unit activity of the gigantocellular tegmental field in the sleep-wakefulness cycle of rats].

作者信息

Gvetadze L B, Mandzhevidze Sh D, Oniani T N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1988 Jan;74(1):32-40.

PMID:3356265
Abstract

Computer analysis and statistical processing of the unit activity showed that the majority of neurons (65.2%) in the gigantocellular tegmental field were discharging with high frequency during active wakefulness and paradoxical sleep as compared to slow-wave sleep in unrestrained rats. 11.6% of the neurons revealed an inverse pattern of activity: they discharged more intensively during slow-wave sleep, their firing rate decreasing during active wakefulness and paradoxical sleep. Some neurons (23.2%) were found which fired intensively during active wakefulness, their firing rate decreasing both in slow-wave and paradoxical sleep. Involvement of the gigantocellular tegmental field in the neurophysiological mechanisms of phases and stages of the sleep-wakefulness cycle is discussed.

摘要

对单位活动的计算机分析和统计处理表明,在自由活动的大鼠中,与慢波睡眠相比,巨细胞被盖区的大多数神经元(65.2%)在主动觉醒和异相睡眠期间高频放电。11.6%的神经元表现出相反的活动模式:它们在慢波睡眠期间放电更强烈,在主动觉醒和异相睡眠期间放电频率降低。发现一些神经元(23.2%)在主动觉醒期间强烈放电,其放电频率在慢波睡眠和异相睡眠中均降低。本文讨论了巨细胞被盖区在睡眠-觉醒周期各阶段神经生理机制中的作用。

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