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胚胎发育过程中软骨内的多胺及其多胺代谢酶

Polyamines and enzymes of polyamines metabolism in the cartilage during embryonic development.

作者信息

Bargoni N, Tazartes O

机构信息

Dipartimento di Medicina e Oncologia Sperimentale, Universitá di Torino, Italy.

出版信息

Int J Biochem. 1988;20(3):317-9. doi: 10.1016/0020-711x(88)90357-6.

DOI:10.1016/0020-711x(88)90357-6
PMID:3356295
Abstract
  1. In chicken embryo cartilage putrescine levels, maximal at day 8, fall by day 16 to a four-fold lower value, which remains unchanged through hatching and in the 12-day-old chick. 2. Spermine and spermidine, initially higher than putrescine, are almost halved between days 8 and 11, and remain constant afterwards. 3. Ornithine decarboxylase is down to 20% of the day 8 value by day 16, and is further reduced in the newly hatched chick. 4. S-Adenosyl-methionine decarboxylase activity shows a 50% reduction between days 8 and 11, and no further changes. 5. Spermidine acetyltransferase activity at day 11 is 30% lower than at day 8, goes back up to the initial level by day 16, and progressively decreases through hatching and the first 12 days of life.
摘要
  1. 在鸡胚软骨中,腐胺水平在第8天达到最高,到第16天降至其四分之一,直至孵化和12日龄雏鸡阶段均保持不变。2. 精胺和亚精胺最初高于腐胺,在第8天至第11天之间几乎减半,此后保持恒定。3. 鸟氨酸脱羧酶到第16天降至第8天值的20%,在新孵化的雏鸡中进一步降低。4. S-腺苷甲硫氨酸脱羧酶活性在第8天至第11天之间降低了50%,之后没有进一步变化。5. 亚精胺乙酰转移酶活性在第11天比第8天低30%,到第16天回升至初始水平,并在孵化和出生后的前12天逐渐下降。

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1
Polyamines and enzymes of polyamines metabolism in the cartilage during embryonic development.胚胎发育过程中软骨内的多胺及其多胺代谢酶
Int J Biochem. 1988;20(3):317-9. doi: 10.1016/0020-711x(88)90357-6.
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Diurnal levels of polyamines and activities of ornithine and S-adenosyl-L-methionine decarboxylases in mouse brain.小鼠脑中多胺的昼夜水平以及鸟氨酸和S-腺苷-L-蛋氨酸脱羧酶的活性
Neurochem Res. 1981 Apr;6(4):377-83. doi: 10.1007/BF00963852.
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Occurrence of ornithine decarboxylase and polyamines in cartilage.软骨中鸟氨酸脱羧酶和多胺的存在情况。
Biochem J. 1977 Feb 15;162(2):347-50. doi: 10.1042/bj1620347.
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Changes in polyamine synthesis and concentrations during chick embryo development.鸡胚发育过程中多胺合成及浓度的变化
J Exp Zool. 1985 Jun;234(3):375-82. doi: 10.1002/jez.1402340307.
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Developmental pattern of ornithine decarboxylase activity, S-adenosylmethionine decarboxylase, and polyamines of rat adrenal glands.大鼠肾上腺鸟氨酸脱羧酶活性、S-腺苷甲硫氨酸脱羧酶及多胺的发育模式
Biol Neonate. 1987;51(5):260-7. doi: 10.1159/000242662.
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Developmental changes in mouse brain polyamine metabolism.小鼠脑内多胺代谢的发育变化。
Neurochem Res. 1982 Dec;7(12):1477-85. doi: 10.1007/BF00965090.
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Expression of a heterologous S-adenosylmethionine decarboxylase cDNA in plants demonstrates that changes in S-adenosyl-L-methionine decarboxylase activity determine levels of the higher polyamines spermidine and spermine.一种异源S-腺苷甲硫氨酸脱羧酶cDNA在植物中的表达表明,S-腺苷-L-甲硫氨酸脱羧酶活性的变化决定了高级多胺亚精胺和精胺的水平。
Plant Physiol. 2002 Aug;129(4):1744-54. doi: 10.1104/pp.010966.
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[Changes in enzyme activity associated with polyamine metabolism in the rat fetal liver during the perinatal period].[围产期大鼠胎肝中与多胺代谢相关的酶活性变化]
Nihon Sanka Fujinka Gakkai Zasshi. 1986 Dec;38(12):2178-86.
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Indirect evidence for a strict negative control of S-adenosyl-L-methionine decarboxylase by spermidine in rat hepatoma cells.在大鼠肝癌细胞中,亚精胺对S-腺苷-L-甲硫氨酸脱羧酶进行严格负调控的间接证据。
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Polyamines and their biosynthetic decarboxylases in various tissues of the young rat during undernutrition.营养不足时幼鼠不同组织中的多胺及其生物合成脱羧酶
Br J Nutr. 1977 Jul;38(1):73-86. doi: 10.1079/bjn19770063.

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