正畸治疗排齐阶段成年女性软组织面型变化的三维几何形态测量研究。

Soft tissue facial changes among adult females during alignment stage of orthodontic treatment: a 3D geometric morphometric study.

机构信息

Stomatological Hospital of Chongqing Medical University China, No. 426 Songshi North Road, Chongqing, China.

Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.

出版信息

BMC Oral Health. 2021 Feb 9;21(1):57. doi: 10.1186/s12903-021-01425-2.

DOI:10.1186/s12903-021-01425-2

PMID:33563265

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7874451/

Abstract

BACKGROUND

To investigate changes in facial morphology during the first six months of orthodontic treatment among adult females receiving orthodontic treatment.

METHODS

43 adult females receiving orthodontic treatment were randomly recruited. 3D facial images were taken at baseline (T0), three months (T1), and six months (T2) after treatment initiation. Spatially dense facial landmarks were digitized to allow for sufficient details in characterization of facial features. 3D geometric morphometrics and multivariate statistics were used to investigate changes in mean and variance of facial shape and facial form associated with treatment.

RESULTS

We observed statistically significant changes in facial shape across the three treatment stages (p = 0.0022). Pairwise comparisons suggested significant changes from T0 to T1 (p = 0.0045) and from T0 to T2 (p = 0.0072). Heatmap visualization indicated that the buccal and temporal region were invaginated while the labial region became protruded with treatment. The magnitude of shape change was 0.009, 0.004, and 0.010 from T0 to T1, T1 to T2, and T0 to T2, respectively, in unit of Procrustes distance. The average magnitude of change per-landmark was 1.32 mm, 0.21 mm, and 1.34 mm, respectively. Changes in mean facial form were not statistically significant (p = 0.1143). No changes in variance of facial shape were observed across treatment stages (p > 0.05).

CONCLUSION

Rate of facial changes was twice as fast during the first three months as that during fourth to sixth month. Buccal and temporal region became invaginated while labial region became protruded with treatment.

摘要

背景

本研究旨在探讨正畸治疗女性成人患者在治疗开始后前 6 个月内的面部形态变化。

方法

本研究共纳入 43 名接受正畸治疗的女性成人患者。在治疗开始时（T0）、治疗 3 个月时（T1）和治疗 6 个月时（T2），拍摄患者的 3D 面部图像。对空间密集的面部标志点进行数字化，以充分描述面部特征。采用 3D 几何形态测量学和多元统计方法，研究治疗相关的面部形状和形态的均值和方差变化。

结果

我们观察到在三个治疗阶段，患者的面部形状均发生了统计学上的显著变化（p = 0.0022）。两两比较显示，T0 至 T1 时（p = 0.0045）和 T0 至 T2 时（p = 0.0072）差异具有统计学意义。热图可视化显示，治疗后颊侧和颞侧区域内陷，唇侧区域突出。T0 至 T1、T1 至 T2 和 T0 至 T2 时，形状变化的幅度分别为 0.009、0.004 和 0.010，以 Procrustes 距离为单位。每个标志点的平均变化幅度分别为 1.32 毫米、0.21 毫米和 1.34 毫米。治疗期间，面部形态的均值变化无统计学意义（p = 0.1143）。治疗各阶段，面部形状的方差无明显变化（p > 0.05）。