Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Centre for Research and Development, Uppsala University/Region Gävleborg, Gävle, Sweden.
NPJ Prim Care Respir Med. 2021 Feb 9;31(1):5. doi: 10.1038/s41533-021-00218-y.
A correct use of inhaler devices is essential in chronic obstructive pulmonary disease (COPD) treatment. Critical errors were studied by analysing 659 video-recorded demonstrations of inhaler technique from 364 COPD patients using six different inhaler device models. The majority of the included patients used two (55%) or more (20%) device models. Overall, 66% of the patients made ≥1 critical error with at least one device model. The corresponding numbers for patients using 1, 2 and ≥3 device models were 43%, 70% and 86%, respectively. The only factor associated with making ≥1 critical error was simultaneous use of two (adjusted odds ratios (aOR) 3.17, 95% confidence interval (95% CI) 1.81, 5.64) or three or more (aOR 8.97, 95% CI 3.93, 22.1) device models. In conclusion, the proportion of patients making critical errors in inhaler technique was substantial, particularly in those using several different device models. To obtain optimal COPD treatment, it is important to assess a patient's inhaler technique and to minimise the number of inhaler device models.
正确使用吸入器装置对于慢性阻塞性肺疾病（COPD）的治疗至关重要。通过分析 364 名 COPD 患者使用六种不同吸入器装置模型进行的 659 次吸入器技术视频记录演示，研究了关键错误。大多数纳入的患者使用了两种（55%）或更多（20%）装置模型。总体而言，66%的患者在至少一种装置模型上犯了≥1 个关键错误。使用 1、2 和≥3 种装置模型的患者的相应数字分别为 43%、70%和 86%。唯一与犯≥1 个关键错误相关的因素是同时使用两种（调整后的优势比[aOR]3.17，95%置信区间[95%CI]1.81，5.64）或三种或更多（aOR 8.97，95%CI 3.93，22.1）装置模型。总之，在吸入器技术方面犯关键错误的患者比例相当大，特别是在使用多种不同装置模型的患者中。为了获得最佳的 COPD 治疗效果，评估患者的吸入器技术并尽量减少吸入器装置模型的数量非常重要。
