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魏斯氏菌:一种具有广阔健康效益的新兴细菌。

Weissella: An Emerging Bacterium with Promising Health Benefits.

机构信息

InovaLeite - Laboratório de Pesquisa em Leites eDerivados, Departamento de Tecnologia de Alimentos, Universidade Federal de Viçosa, Viçosa, 36570900, MG, Brazil.

UMR Transfrontalière BioEcoAgro1158, Univ. Lille, INRAE, Univ. Liège, UPJV, YNCREA, Univ. Artois, Univ. Littoral Côte D'Opale, ICV - Institut Charles Viollette, 59000, Lille, France.

出版信息

Probiotics Antimicrob Proteins. 2021 Aug;13(4):915-925. doi: 10.1007/s12602-021-09751-1. Epub 2021 Feb 9.

Abstract

Weissella strains have been the subject of much research over the last 5 years because of the genus' technological and probiotic potential. Certain strains have attracted the attention of the pharmaceutical, medical, and food industries because of their ability to produce antimicrobial exopolysaccharides (EPSs). Moreover, Weissella strains are able to keep foodborne pathogens in check because of the bacteriocins, hydrogen peroxide, and organic acids they can produce; all listed have recognized pathogen inhibitory activities. The Weissella genus has also shown potential for treating atopic dermatitis and certain cancers. W. cibaria, W. confusa, and W. paramesenteroides are particularly of note because of their probiotic potential (fermentation of prebiotic fibers) and their ability to survive in the gastrointestinal tract. It is important to note that most of the Weissella strains with these health-promoting properties have been shown to be save safe, due to the absence or the low occurrence of virulence or antibiotic-resistant genes. A large number of scientific studies continue to report on and to support the use of Weissella strains in the food and pharmaceutical industries. This review provides an overview of these studies and draws conclusions for future uses of this rich and previously unexplored genus.

摘要

过去 5 年来,由于魏斯氏菌属具有技术和益生菌潜力,该属一直是许多研究的主题。某些菌株因其能够产生抗菌胞外多糖 (EPS) 而引起了制药、医疗和食品行业的关注。此外,由于魏斯氏菌能够产生细菌素、过氧化氢和有机酸,因此能够控制食源性病原体;所有这些都具有公认的抑制病原体的活性。魏斯氏菌属在治疗特应性皮炎和某些癌症方面也显示出潜力。由于其益生菌潜力(发酵益生元纤维)和在胃肠道中生存的能力,W. cibaria、W. confusa 和 W. paramesenteroides 尤为值得注意。需要注意的是,由于大多数具有这些促进健康特性的魏斯氏菌属菌株的毒力或抗生素耐药基因缺失或低发生,因此被证明是安全的。大量科学研究继续报告并支持在食品和制药行业中使用魏斯氏菌属。本综述概述了这些研究,并为该丰富且以前未开发的属的未来用途得出结论。

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