Department of Gastroenterology, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
Clin J Gastroenterol. 2021 Jun;14(3):827-830. doi: 10.1007/s12328-021-01354-1. Epub 2021 Feb 10.
A 25-year-old woman with fever and epigastric pain was referred to our hospital. Blood examination showed significant liver dysfunction, markedly high C-reactive protein (CRP 19.1 mg/dL) and procalcitonin (48.3 ng/mL) levels. Dynamic computed tomography showed a tumor approximately 120 mm in size in the right lobe of the liver, but with no abscess formation. The patient was hospitalized and started on antibiotics; her CRP level improved, but the procalcitonin level did not decrease. Histopathological examination of the liver tumor biopsy revealed fibrolamellar hepatocellular carcinoma (FLC). Positive staining of the FLC with an anti-procalcitonin antibody suggested the production of procalcitonin.
一位 25 岁女性，因发热和上腹痛就诊于我院。血液检查显示显著肝功能障碍，C 反应蛋白（CRP 19.1mg/dL）和降钙素原（48.3ng/mL）水平显著升高。动态计算机断层扫描显示肝右叶约 120mm 大小的肿瘤，但无脓肿形成。患者住院并开始使用抗生素；她的 CRP 水平有所改善，但降钙素原水平没有下降。肝肿瘤活检的组织病理学检查显示纤维板层肝细胞癌（FLC）。抗降钙素原抗体对 FLC 的阳性染色提示降钙素原的产生。
