Lafage Renaud, Schwab Frank, Elysee Jonathan, Smith Justin S, Alshabab Basel Sheikh, Passias Peter, Klineberg Eric, Kim Han Jo, Shaffrey Christopher, Burton Douglas, Gupta Munish, Mundis Gregory M, Ames Christopher, Bess Shay, Lafage Virginie
Spine Service, Hospital for Special Surgery, New York, NY, USA.
Department of Neurosurgery, University of Virginia Medical Center, Charlottesville, VA, USA.
Global Spine J. 2022 Oct;12(8):1761-1769. doi: 10.1177/2192568220988504. Epub 2021 Feb 11.
Retrospective cohort study.
Establish simultaneous focal and regional corrective guidelines accounting for reciprocal global and pelvic compensation.
433 ASD patients (mean age 62.9 yrs, 81.3% F) who underwent corrective realignment (minimum L1-pelvis) were included. Sagittal parameters, and segmental and regional Cobb angles were assessed pre and post-op. Virtual postoperative alignment was generated by combining post-op alignment of the fused spine with the pre-op alignment on the unfused thoracic kyphosis and the pre-op pelvic retroversion. Regression models were then generated to predict the relative impact of segmental (L4-L5) and regional (L1-L4) corrections on PT, SVA (virtual), and TPA.
Baseline analysis revealed distal (L4-S1) lordosis of 33 ± 15°, flat proximal (L1-L4) lordosis (1.7 ± 17°), and segmental kyphosis from L2-L3 to T10-T11. Post-op, there was no mean change in distal lordosis (L5-S1 decreased by 2°, and L4-L5 increased by 2°), while the more proximal lordosis increased by 18 ± 16°. Regression formulas revealed that Δ10° in distal lordosis resulted in Δ10° in TPA, associated with Δ100 mm in SVA or Δ3° in PT; Δ10° in proximal lordosis yielded Δ5° in TPA associated with Δ50 mm in SVA; and finally Δ10° in thoraco-lumbar junction yielded Δ2.5° in TPA associated with Δ25 mm in SVA and no impact on PT correction.
Overall impact of lumbar lordosis restoration is critically determined by location of correction. Distal correction leads to a greater impact on global alignment and pelvic retroversion. More specifically, it can be assumed that 1° L4-S1 lordosis correction produces 1° change in TPA / 10 mm change in SVA and 0.5° in PT.
回顾性队列研究。
制定同时考虑整体和骨盆相互代偿的局部及区域矫正指南。
纳入433例接受矫正复位(至少L1 - 骨盆)的成人脊柱畸形(ASD)患者(平均年龄62.9岁,女性占81.3%)。评估矢状面参数以及节段和区域Cobb角的术前和术后情况。通过将融合脊柱的术后对线与未融合胸椎后凸的术前对线及术前骨盆后倾相结合,生成虚拟术后对线。然后建立回归模型,以预测节段性(L4 - L5)和区域性(L1 - L4)矫正对骨盆倾斜度(PT)、矢状面垂直轴(SVA,虚拟)和胸椎后凸角(TPA)的相对影响。
基线分析显示,远端(L4 - S1)前凸为33±15°,近端(L1 - L4)前凸较平(1.7±17°),且从L2 - L3到T10 - T11存在节段性后凸。术后,远端前凸无平均变化(L5 - S1减少2°,L4 - L5增加2°),而近端前凸增加了18±16°。回归公式显示,远端前凸每增加10°,TPA增加10°,SVA增加100毫米或PT增加3°;近端前凸每增加10°,TPA增加5°,SVA增加50毫米;最后,胸腰段交界处每增加10°,TPA增加2.5°,SVA增加25毫米,且对PT矫正无影响。
腰椎前凸恢复的总体影响关键取决于矫正位置。远端矫正对整体对线和骨盆后倾的影响更大。更具体地说,可以假设L4 - S1前凸矫正1°会导致TPA变化1°/SVA变化10毫米以及PT变化0.5°。