《乳糜泻生活质量问卷（CDQOL）的波斯语翻译与验证》。
The Persian Translation and validation of the celiac disease quality of life questionnaire (CDQOL).
机构信息
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Road Traffic Injury Research Center, Department of Epidemiology and Biostatistics, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Health Qual Life Outcomes. 2021 Feb 10;19(1):52. doi: 10.1186/s12955-021-01694-z.
BACKGROUND
Considering the importance of having a celiac disease-specific measure of the quality of life (QOL) in Persian, the present study aimed to translate the celiac disease quality of life questionnaire (CDQOL) into Persian and evaluate its psychometric properties.
METHODS
In this cross-sectional study, the Forward-Backward translation method was used. The content validation ratio (CVR) and the content validity index (CVI) were used for content validity assessment. The construct validity was assessed by exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) on 220 celiac patients who were selected randomly from the celiac disease (CD) registry database. The correlations between the result of the Persian version of CDQOL (PCDQOL), self-rated QOL, and short form-36 (SF36) were analyzed using the Pearson correlation test. The internal consistency and test-retest reliability were measured through Cronbach's alpha and intraclass correlation coefficient (ICC).
RESULTS
In the present study, 220 celiac patients with a mean age of 35.54 ± 10.29 years participated. The mean CVI, CVR, and impact score of PCDQOL were 0.98, 0.96, and 4.82 respectively. Using EFA, four factors have extracted that had a good fit in CFA (Chi-square/DF = 1.74, RMSEA: 0.08, and CFI: 0.90, and NFI: 0.90). The results showed that there was a moderate to high correlation between PCDQOL, SF36 (r: 0.587, p = 0.02), and self-rated QOL (r: 0.64, p < 0.001). The questionnaire had high internal consistency (Cronbach alpha: 0.93) and test-retest reliability (ICC: 0.96 [0.86-0.99]).
CONCLUSION
The PCDQOL questionnaire could be used by physicians and nutritionists to assess HRQOL in celiac patients in Iran.
背景
考虑到在波斯语中拥有一种针对乳糜泻患者生活质量（QOL）的特异性测量方法的重要性，本研究旨在将乳糜泻生活质量问卷（CDQOL）翻译成波斯语，并评估其心理测量特性。
方法
在这项横断面研究中，采用了向前-向后翻译法。内容效度比（CVR）和内容效度指数（CVI）用于内容效度评估。通过对从乳糜泻（CD）登记数据库中随机选择的 220 名乳糜泻患者进行探索性因子分析（EFA）和验证性因子分析（CFA），评估了结构效度。使用 Pearson 相关检验分析了波斯语版 CDQOL（PCDQOL）的结果与自我报告 QOL 和 SF36 之间的相关性。通过 Cronbach 的 alpha 和组内相关系数（ICC）测量内部一致性和重测信度。
结果
本研究共纳入 220 名乳糜泻患者，平均年龄为 35.54±10.29 岁。PCDQOL 的平均 CVI、CVR 和影响评分分别为 0.98、0.96 和 4.82。使用 EFA，提取出四个因子，在 CFA 中具有良好的拟合度（卡方/自由度=1.74，RMSEA：0.08，CFI：0.90，NFI：0.90）。结果表明，PCDQOL 与 SF36（r：0.587，p=0.02）和自我报告 QOL（r：0.64，p<0.001）之间存在中度至高度相关性。该问卷具有较高的内部一致性（Cronbach alpha：0.93）和重测信度（ICC：0.96[0.86-0.99]）。
结论
PCDQOL 问卷可由伊朗的医生和营养师用于评估乳糜泻患者的 HRQOL。
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