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Sinbase 2.0:一个用于研究多组学的更新数据库 。 (你提供的原文最后似乎不完整)

Sinbase 2.0: An Updated Database to Study Multi-Omics in .

作者信息

Wang Liwen, Yu Jingyin, Zhang Yanxin, You Jun, Zhang Xiurong, Wang Linhai

机构信息

Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Ministry of Agriculture, No.2 Xudong Second Road, Wuhan 430062, China.

Shandong Luyan Agricultural Co., LTC, Jinan 250100, China.

出版信息

Plants (Basel). 2021 Jan 30;10(2):272. doi: 10.3390/plants10020272.

DOI:10.3390/plants10020272
PMID:33573226
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7911383/
Abstract

Sesame is one of the oldest oil crops in the world and is widely grown in the tropical and subtropical areas of Asia, Africa and America. Upon the completion of the sesame reference genome version 1.0, we launched Sinbase 1.0 as an integrated database for genomic and bioinformatics analyses. Recently, an upgraded version (version 2.0) of the genome sequence was released. In addition, large numbers of multi-omics data have been generated on sesame, but a comprehensive database that integrates these resources for the community has been lacking until now. Here, we developed an interactive and comprehensive sesame multi-omics database, Sinbase 2.0, which provides information of the sesame updated genome containing 13 chromosomes, 3 genetic linkage maps, 5 intra- and 6 inter-species comparative genomics, 1 genomic variation analysis, 5 transcriptome data, 1 proteome, 31 functional markers, 175 putative functional genes, and 54 QTLs detected for important agronomic traits. Moreover, Sinbase 2.0 has been enriched with novel user-friendly computational tools. All datasets of Sinbase 2.0 can be downloaded online conveniently. Sinbase 2.0 will be updated regularly with new available sesame multi-omics data and can be accessed freely via Sinbase 2.-Sesame Muti-Omics Database. We expect that Sinbase 2.0, similarly to the previous version, will continue to make a major contribution to advance sesame research towards a better understanding of its biology and genetic improvement, as well as comparative genomics and evolutionary biology.

摘要

芝麻是世界上最古老的油料作物之一,广泛种植于亚洲、非洲和美洲的热带和亚热带地区。在芝麻参考基因组版本1.0完成后,我们推出了Sinbase 1.0作为基因组和生物信息学分析的综合数据库。最近,基因组序列的升级版(版本2.0)发布了。此外,已经产生了大量关于芝麻的多组学数据,但到目前为止,一直缺乏一个为该领域整合这些资源的综合数据库。在此,我们开发了一个交互式的综合性芝麻多组学数据库Sinbase 2.0,它提供了包含13条染色体的芝麻更新基因组信息、3个遗传连锁图谱、5个种内和6个种间比较基因组学、1个基因组变异分析、5个转录组数据、1个蛋白质组、31个功能标记、175个推定功能基因以及针对重要农艺性状检测到的54个QTL。此外,Sinbase 2.0还丰富了新颖的用户友好型计算工具。Sinbase 2.0的所有数据集都可以方便地在线下载。Sinbase 2.0将定期更新可用的芝麻多组学新数据,并可通过Sinbase 2. - 芝麻多组学数据库免费访问。我们期望Sinbase 2.0与之前的版本一样,将继续为推动芝麻研究做出重大贡献,以更好地理解其生物学特性和遗传改良,以及比较基因组学和进化生物学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af2/7911383/283962fdb5c2/plants-10-00272-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af2/7911383/640c1a57fd14/plants-10-00272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af2/7911383/283962fdb5c2/plants-10-00272-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af2/7911383/640c1a57fd14/plants-10-00272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af2/7911383/283962fdb5c2/plants-10-00272-g002.jpg

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Development of Highly Informative Genome-Wide Single Sequence Repeat Markers for Breeding Applications in Sesame and Construction of a Web Resource: SisatBase.用于芝麻育种应用的高信息量全基因组单序列重复标记的开发及网络资源SisatBase的构建
Front Plant Sci. 2017 Aug 22;8:1470. doi: 10.3389/fpls.2017.01470. eCollection 2017.
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Transcriptomic, biochemical and physio-anatomical investigations shed more light on responses to drought stress in two contrasting sesame genotypes.
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5
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PMDBase: a database for studying microsatellite DNA and marker development in plants.PMDBase:一个用于研究植物微卫星DNA和标记开发的数据库。
Nucleic Acids Res. 2017 Jan 4;45(D1):D1046-D1053. doi: 10.1093/nar/gkw906. Epub 2016 Oct 12.
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